Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

Obesity is a risk factor for cancer development and is associated with poor prognosis in
multiple tumor types. The positive energy balance linked with obesity induces a variety of …

The incidence of endometrial cancer is increasing, and the age of onset is younger than in
prior years. Although endometrial cancer still occurs more commonly in older women, for …

Cancer is a major disease with a high mortality rate worldwide. In many countries, cancer is
considered to be the second most common cause of death after cardiovascular disease. The …

Obesity, defined as the abnormal or excessive expansion of white adipose tissue, has
reached pandemic proportions and is recognized as an important health concern since it is …

Obesity is the strongest risk factor for endometrial cancer (EC). To inform targeted screening
and prevention strategies, we assessed the impact of obesity and subsequent bariatric …

Obesity and upper-body fat distribution are independent, cardiometabolic risk factors but
whether they also display comparable associations with cancer risk is unknown. We …

Endometrial cancer (EC) is the fifth most common cancer in women worldwide. Global
estimates show rising incidence rates in both developed and developing countries. Most …

Background The role of insulin resistance as a mediator in the association of body mass
index (BMI) with site-specific cancer risk has, to our knowledge, never been systematically …

Cancers are regarded as one of the main causes of death and result in high health burden
worldwide. The management of cancer include chemotherapy, surgery and radiotherapy …