Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

Stroke is associated with a high disability and fatality rate, and adversely affects the quality
of life of patients and their families. Traditional Chinese Medicine (TCM) has been used …

Ischemic stroke is an acute and severe neurological disease with high mortality and
disability rates worldwide. Polymerase I and transcript release factor (PTRF) plays a pivotal …

Ethnopharmacological relevance Stroke is one of the leading causes of death and disability.
The only FDA-approved therapy for treating stroke is tissue plasminogen activator (tPA) …

The brain-derived neurotrophic factor/tropomyosin receptor kinase B/cAMP response
element-binding protein (BDNF/TrkB/CREB) signaling pathway is a critical therapeutic target …

The pathogenesis of ischemic stroke is complex, and PI3K/Akt signaling is considered to
play a crucial role in it. The PI3K/Akt pathway regulates inflammation, oxidative stress …

Ischemic stroke (IS) is an acute cerebrovascular disease caused by sudden arterial
occlusion, which is characterized by a high morbidity, mortality, and disability rate. It is one of …

Abstract Background Buyang Huanwu decoction (BYHWD) is a famous traditional Chinese
formula that has been widely prescribed for sequelae of stroke in China. However, the …

Intestinal microbiota is a unique ecosystem, known as the" second genome" of human
beings. With the widespread application of next generation sequencing (NGS), especially 16 …

Background Ischemic stroke (IS) is a leading cause of death and severe long-term disability
worldwide. Over the past few decades, considerable progress has been made in anti …