Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

Y Shi, L Du, L Lin, Y Wang - Nature reviews Drug discovery, 2017 - nature.com
Mesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), exist in many
tissues and are known to actively migrate to sites of tissue injury, where they participate in …

Exosomal microRNAs derived from mesenchymal stem cells: cell-to-cell messages

K Asgarpour, Z Shojaei, F Amiri, J Ai… - Cell Communication and …, 2020 - Springer
Exosomes are extracellular vesicles characterized by their size, source, release mechanism
and contents. MicroRNAs (miRNAs) are single stranded non-coding RNAs transcribed from …

MicroRNA: A novel target of curcumin in cancer therapy

H Mirzaei, A Masoudifar, A Sahebkar… - Journal of cellular …, 2018 - Wiley Online Library
Curcumin is known as a natural dietary polyphenol which is extracted from Curcuma longa
L. It has been shown that curcumin has a variety of pharmacological effects such as …

Stem cell therapy: a new therapeutic option for cardiovascular diseases

NH Goradel, FG Hour, B Negahdari… - Journal of cellular …, 2018 - Wiley Online Library
Cardiovascular diseases are known as one of major causes of morbidity and mortality
worldwide. Despite the many advancement in therapies are associated with cardiovascular …

The multifaceted role of mesenchymal stem cells in cancer

M Timaner, KK Tsai, Y Shaked - Seminars in cancer biology, 2020 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stem cells derived from the mesoderm that
give rise to several mesenchymal lineages, including osteoblasts, adipocytes, chondrocytes …

MicroRNA: relevance to stroke diagnosis, prognosis, and therapy

H Mirzaei, F Momeni, L Saadatpour… - Journal of cellular …, 2018 - Wiley Online Library
Stroke is a life‐threatening disease that accounts for a considerable burden of mortality in
both developing and developed world. Identification of specific biomarkers for stroke and its …

TGF-β1-modified MSC-derived exosomal miR-135b attenuates cartilage injury via promoting M2 synovial macrophage polarization by targeting MAPK6

R Wang, B Xu - Cell and tissue research, 2021 - Springer
Osteoarthritis (OA) is the most common joint disease with an unsatisfactory therapy outcome
and characterized by the degradation of articular cartilage and synovial inflammation. Here …

MiR‐21: A key player in glioblastoma pathogenesis

MS Masoudi, E Mehrabian… - Journal of cellular …, 2018 - Wiley Online Library
Glioblastoma multiform (GBM) is one of common cancers worldwide which has high rate
among various populations. Despite serious efforts worldwide, GBM remains a deadly …

Diagnostic and therapeutic potential of exosomes in cancer: the beginning of a new tale?

H Mirzaei, A Sahebkar, MR Jaafari… - Journal of cellular …, 2017 - Wiley Online Library
Exosomes have emerged as one of the main players in intercellular communication. These
small nano‐sized particles have many roles in various physiological pathways in normal …

Therapeutic application of multipotent stem cells

H Mirzaei, A Sahebkar, LS Sichani… - Journal of cellular …, 2018 - Wiley Online Library
Cell therapy is an emerging fields in the treatment of various diseases such as
cardiovascular, pulmonary, hepatic, and neoplastic diseases. Stem cells are an integral tool …