Introduction: Over the past decade, loop-mediated isothermal amplification (LAMP)
technology has played an important role in molecular diagnostics. Amongst numerous …

Context The role of percutaneous renal tumour biopsy (RTB) remains controversial due to
uncertainties regarding its diagnostic accuracy and safety. Objective We performed a …

The control of viral outbreaks requires nucleic acid diagnostic tests that are sensitive, simple
and fast. Here, we report a highly sensitive and specific one-pot assay for the fluorescence …

Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Insufficient awareness of the centrality of pathology and laboratory medicine (PALM) to a
functioning health-care system at policy and governmental level, with the resultant …

Loop-mediated isothermal amplification (LAMP) is an isothermal nucleic acid amplification
(iNAAT) technique known for its simplicity, sensitivity and speed. Its low-cost feature has …

Current point-of-care lateral flow immunoassays, such as the home pregnancy test, rely on
proteins as detection units (eg antibodies) to sense for analytes. Glycans play a fundamental …

Background CRISPR-based diagnostics are a new class of highly sensitive and specific
assays with multiple applications in infectious disease diagnosis. SHERLOCK, or Specific …

SUMMARY Point-of-care (POC) laboratories that deliver rapid diagnoses of infectious
diseases were invented to balance the centralization of core laboratories. POC laboratories …

The Middle East respiratory syndrome coronavirus (MERS-CoV), an emerging human
coronavirus, causes severe acute respiratory illness with a 35% mortality rate. In light of the …