Polymeric long-acting drug delivery systems (LADDS) for treatment of chronic diseases: Inserts, patches, wafers, and implants
Non-oral long-acting drug delivery systems (LADDS) encompass a range of technologies for
precisely delivering drug molecules into target tissues either through the systemic circulation …
precisely delivering drug molecules into target tissues either through the systemic circulation …
[HTML][HTML] Site-specific targeted drug delivery systems for the treatment of inflammatory bowel disease
X Li, C Lu, Y Yang, C Yu, Y Rao - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis and
manifests as a complex and dysregulated immune response. To date, there is no cure for …
manifests as a complex and dysregulated immune response. To date, there is no cure for …
Carboxymethyl chitosan microspheres loaded hyaluronic acid/gelatin hydrogels for controlled drug delivery and the treatment of inflammatory bowel disease
S Zhang, L Kang, S Hu, J Hu, Y Fu, Y Hu… - International Journal of …, 2021 - Elsevier
A major drawback of oral treatment of inflammatory bowel disease (IBD) is the non-specific
distribution of drugs during long-term treatment. Despite its effectiveness as an anti …
distribution of drugs during long-term treatment. Despite its effectiveness as an anti …
A probiotic spore‐based oral autonomous nanoparticles generator for cancer therapy
Q Song, C Zheng, J Jia, H Zhao, Q Feng… - Advanced …, 2019 - Wiley Online Library
Spores, the dormant life forms of probiotics, can germinate to metabolically active vegetative
cells with the disintegration of their hydrophobic protein coat in the intestinal …
cells with the disintegration of their hydrophobic protein coat in the intestinal …
Local delivery of macromolecules to treat diseases associated with the colon
Current treatments for intestinal diseases including inflammatory bowel diseases, irritable
bowel syndrome, and colonic bacterial infections are typically small molecule oral dosage …
bowel syndrome, and colonic bacterial infections are typically small molecule oral dosage …
Oral delivery of curcumin via multi-bioresponsive polyvinyl alcohol and guar gum based double-membrane microgels for ulcerative colitis therapy
Y Hu, S Zhang, Z Wen, H Fu, J Hu, X Ye, L Kang… - International Journal of …, 2022 - Elsevier
Anti-inflammatory drugs for ulcerative colitis (UC) treatment should specifically penetrate
and accumulate in the colon tissue. Herein, a multi-bioresponsive anti-inflammatory drug …
and accumulate in the colon tissue. Herein, a multi-bioresponsive anti-inflammatory drug …
Macrophages-targeting mannosylated nanoparticles based on inulin for the treatment of inflammatory bowel disease (IBD)
Q Sun, M Arif, Z Chi, G Li, CG Liu - International Journal of Biological …, 2021 - Elsevier
In the present experimental series, we have developed a novel nanocomposite to target
activated macrophages in the colon with real time imaging and therapeutic capabilities. This …
activated macrophages in the colon with real time imaging and therapeutic capabilities. This …
The potential of Fe‐based magnetic nanomaterials for the agriculture sector
Iron‐based magnetic nanoparticles (MNPs) have been studied extensively for the past few
decades. They have been applied in various applications, particularly in the biomedical …
decades. They have been applied in various applications, particularly in the biomedical …
In Vitro Methods to Study Colon Release: State of the Art and An Outlook on New Strategies for Better In-Vitro Biorelevant Release Media
The primary focus of this review is a discussion regarding in vitro media for colon release,
but we also give a brief overview of colon delivery and the colon microbiota as a baseline for …
but we also give a brief overview of colon delivery and the colon microbiota as a baseline for …
Site-directed non-covalent polymer-drug complexes for inflammatory bowel disease (IBD): formulation development, characterization and pharmacological evaluation
SS Kesharwani, R Ahmad, MA Bakkari… - Journal of Controlled …, 2018 - Elsevier
Abstract Inflammatory Bowel Diseases (IBD) is a debilitating condition that affects~ 70,000
new people every year and has been described as “an expensive disease with no known …
new people every year and has been described as “an expensive disease with no known …