Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease

Y Inoue, F Shue, G Bu, T Kanekiyo - Molecular neurodegeneration, 2023 - Springer
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

Diagnosis of cerebral amyloid angiopathy: evolution of the Boston criteria

SM Greenberg, A Charidimou - Stroke, 2018 - Am Heart Assoc
492 Stroke February 2018 lobar hemorrhages required for probable CAA, or alternatively
preclude probable CAA if in deep territories. The rationale for counting all types of …

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

A Charidimou, G Boulouis, MP Frosch… - The Lancet …, 2022 - thelancet.com
Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …

Emerging concepts in sporadic cerebral amyloid angiopathy

A Charidimou, G Boulouis, ME Gurol, C Ayata… - Brain, 2017 - academic.oup.com
Sporadic cerebral amyloid angiopathy is a common, well-defined small vessel disease and
a largely untreatable cause of intracerebral haemorrhage and contributor to age-related …

Prevalence of cerebral amyloid angiopathy: a systematic review and meta‐analysis

L Jäkel, AM De Kort, CJM Klijn… - Alzheimer's & …, 2022 - Wiley Online Library
Reported prevalence estimates of sporadic cerebral amyloid angiopathy (CAA) vary widely.
CAA is associated with cognitive dysfunction and intracerebral hemorrhage, and linked to …

Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

MCZ Zotin, L Sveikata, A Viswanathan… - Current opinion in …, 2021 - journals.lww.com
SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …

Prevention of stroke in patients with silent cerebrovascular disease: a scientific statement for healthcare professionals from the American Heart Association/American …

EE Smith, G Saposnik, GJ Biessels, FN Doubal… - Stroke, 2017 - Am Heart Assoc
Two decades of epidemiological research shows that silent cerebrovascular disease is
common and is associated with future risk for stroke and dementia. It is the most common …

Hemorrhagic stroke

A Montaño, DF Hanley, JC Hemphill III - Handbook of clinical neurology, 2021 - Elsevier
Hemorrhagic stroke comprises about 20% of all strokes, with intracerebral hemorrhage
(ICH) being the most common type. Frequency of ICH is increased where hypertension is …

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

D Wilson, G Ambler, KJ Lee, JS Lim… - The Lancet …, 2019 - thelancet.com
Background Cerebral microbleeds are a neuroimaging biomarker of stroke risk. A crucial
clinical question is whether cerebral microbleeds indicate patients with recent ischaemic …

The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice

G Banerjee, R Carare, C Cordonnier… - Journal of Neurology …, 2017 - jnnp.bmj.com
Cerebral amyloid angiopathy (CAA) has never been more relevant. The last 5 years have
seen a rapid increase in publications and research in the field, with the development of new …