Epididymal contribution to male infertility: An overlooked problem

S Elbashir, Y Magdi, A Rashed, R Henkel… - Andrologia, 2021 - Wiley Online Library
The diagnosis and treatment of male infertility, excluding assisted conception, are limited
because of, but not limited to, poor understanding of sperm post‐testicular development and …

Interpreting histopathology in the epididymis

W De Grava Kempinas, GR Klinefelter - Spermatogenesis, 2014 - Taylor & Francis
While most of this Special Issue is devoted to the testis (which is where most drug and
chemically induced toxicity of the male reproductive tract is identified), being able to …

Morphologic manifestations of testicular and epididymal toxicity

JD Vidal, KM Whitney - Spermatogenesis, 2014 - Taylor & Francis
Histopathologic examination of the testis is the most sensitive means to detect effects on
spermatogenesis; however, the complexity of testicular histology, interrelatedness of cell …

Paternal low-dose benzo (a) pyrene exposure in rats impairs sexual development and fertility of the paternal lineage in F2 generation: A transgenerational study

BC Jorge, J Stein, ACC Reis, JN Bueno… - Toxicology, 2023 - Elsevier
Abstract The field of Paternal Origins of Health and Disease (POHaD) is highly relevant but
remains under-explored. The F2 generation from males indirectly exposed (F1-via germ …

Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates

J Robitaille, VS Langlois - General and comparative endocrinology, 2020 - Elsevier
In 1974, a lack of 5α-dihydrotestosterone (5α-DHT), the most potent androgen across
species except for fish, was shown to be the origin of a type of pseudohermaphrodism in …

[HTML][HTML] Green Brazilian propolis effects on sperm count and epididymis morphology and oxidative stress

C Capucho, R Sette, F de Souza Predes… - Food and chemical …, 2012 - Elsevier
Basal generation of reactive oxygen species (ROS) is essential for male reproductive
function, whereas high ROS levels may be linked to low quality of sperm and male infertility …

Comparative effects of finasteride and minoxidil on the male reproductive organs: A systematic review of in vitro and in vivo evidence

FFV Santana, AA Lozi, RV Gonçalves, J Da Silva… - Toxicology and Applied …, 2023 - Elsevier
Finasteride and minoxidil are medicaments commonly prescribed for treating benign
prostatic hyperplasia (BPA), hypertension, and/or androgenetic alopecia (AGA). The …

[HTML][HTML] A decrease of docosahexaenoic acid in testes of mice fed a high-fat diet is associated with impaired sperm acrosome reaction and fertility

J Buñay, LM Gallardo, JL Torres-Fuentes… - Asian Journal of …, 2021 - journals.lww.com
Obesity is a major worldwide health problem that is related to most chronic diseases,
including male infertility. Owing to its wide impact on health, mechanisms underlying obesity …

[HTML][HTML] The Possible Role of Prescribing Medications, Including Central Nervous System Drugs, in Contributing to Male-Factor Infertility (MFI): Assessment of the …

S Baldini, A Khattak, P Capogrosso, G Antonini, F Dehò… - Brain Sciences, 2023 - mdpi.com
Background: A wide range of medications may have a possible role in the development of
male-factor infertility (MFI), including various antineoplastic agents, testosterone/anabolic …

Acute effects of atrazine on the immunoexpressions of Sertoli and germ cells molecular markers, cytokines, chemokines, and sex hormones levels in mice testes and …

SO Abarikwu, JLP Coimbra, G Campolina-Silva… - Chemosphere, 2024 - Elsevier
Atrazine is currently one of the most commonly used agrochemicals in the United States and
elsewhere. Here, we studied the immunoexpression of molecular markers of mammalian …