Lung MRI with hyperpolarised gases: current & future clinical perspectives
The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT
remains the gold-standard for structural lung imaging in many clinical indications, technical …
remains the gold-standard for structural lung imaging in many clinical indications, technical …
Time to get serious about the detection and monitoring of early lung disease in cystic fibrosis
KJ Bayfield, TA Douglas, T Rosenow, JC Davies… - Thorax, 2021 - thorax.bmj.com
Structural and functional defects within the lungs of children with cystic fibrosis (CF) are
detectable soon after birth and progress throughout preschool years often without overt …
detectable soon after birth and progress throughout preschool years often without overt …
129Xe and Free‐Breathing 1H Ventilation MRI in Patients With Cystic Fibrosis: A Dual‐Center Study
H Marshall, A Voskrebenzev, LJ Smith… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Free‐breathing 1H ventilation MRI shows promise but only single‐center
validation has yet been performed against methods which directly image lung ventilation in …
validation has yet been performed against methods which directly image lung ventilation in …
Inter‐and intravisit repeatability of free‐breathing MRI in pediatric cystic fibrosis lung disease
Purpose The purpose of this study is to assess the intra‐and interscan repeatability of free‐
breathing phase‐resolved functional lung (PREFUL) MRI in stable pediatric cystic fibrosis …
breathing phase‐resolved functional lung (PREFUL) MRI in stable pediatric cystic fibrosis …
Lung Function in Patients with Cystic Fibrosis before and during CFTR-Modulator Therapy Using 3D Ultrashort Echo Time MRI
JF Heidenreich, PJ Kuhl, JP Grunz, R Hendel, C Metz… - Radiology, 2023 - pubs.rsna.org
Background The triple combination of the cystic fibrosis transmembrane regulator (CFTR)
modulators elexacaftor, tezacaftor, and ivacaftor (hereafter, elexacaftor/tezacaftor/ivacaftor) …
modulators elexacaftor, tezacaftor, and ivacaftor (hereafter, elexacaftor/tezacaftor/ivacaftor) …
MR imaging of the airways
J Biederer - The British Journal of Radiology, 2023 - academic.oup.com
The need for airway imaging is defined by the limited sensitivity of common clinical tests like
spirometry, lung diffusion (DLCO) and blood gas analysis to early changes of peripheral …
spirometry, lung diffusion (DLCO) and blood gas analysis to early changes of peripheral …
Improving Xenon‐129 lung ventilation image SNR with deep‐learning based image reconstruction
NJ Stewart, J de Arcos, AM Biancardi… - Magnetic …, 2024 - Wiley Online Library
Purpose To evaluate the feasibility and utility of a deep learning (DL)‐based reconstruction
for improving the SNR of hyperpolarized 129Xe lung ventilation MRI. Methods 129Xe lung …
for improving the SNR of hyperpolarized 129Xe lung ventilation MRI. Methods 129Xe lung …
Image Phenotyping of Preterm-Born Children Using Hyperpolarized 129Xe Lung Magnetic Resonance Imaging and Multiple-Breath Washout
Rationale: Preterm birth is associated with low lung function in childhood, but little is known
about the lung microstructure in childhood. Objectives: We assessed the differential …
about the lung microstructure in childhood. Objectives: We assessed the differential …
Monitoring early stage lung disease in cystic fibrosis
Monitoring early stage lung disease in cystic fibrosis : Current Opinion in Pulmonary
Medicine Monitoring early stage lung disease in cystic fibrosis : Current Opinion in …
Medicine Monitoring early stage lung disease in cystic fibrosis : Current Opinion in …
The impact of segmentation on whole‐lung functional MRI quantification: repeatability and reproducibility from multiple human observers and an artificial neural …
C Willers, G Bauman, S Andermatt… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To investigate the repeatability and reproducibility of lung segmentation and their
impact on the quantitative outcomes from functional pulmonary MRI. Additionally, to validate …
impact on the quantitative outcomes from functional pulmonary MRI. Additionally, to validate …