Targeting aberrant amino acid metabolism for pancreatic cancer therapy: Opportunities for nanoparticles
X Zang, K Lei, J Wang, R Gong, C Gao, Z Jing… - Chemical Engineering …, 2024 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal malignancies with
insidious initiation and early metastasis. The autonomous reprogramming of amino acid …
insidious initiation and early metastasis. The autonomous reprogramming of amino acid …
The Mechanism of Cancer-Depression Comorbidity
JW Huang, CA Cao, WH Zheng, CR Jia, X Liu, SQ Gao… - Neuroscience, 2024 - Elsevier
Cancer and depression are closely interrelated, particularly in patients with advanced
cancer, who often present with comorbid anxiety and depression for various reasons …
cancer, who often present with comorbid anxiety and depression for various reasons …
Poor access to mental healthcare is associated with worse postoperative outcomes among patients with gastrointestinal cancer
Background Mental health has an important role in the care of cancer patients, and access
to mental health services may be associated with improved outcomes. Thus, poor access to …
to mental health services may be associated with improved outcomes. Thus, poor access to …
Level of selected exponents of the kynurenine pathway in patients diagnosed with depression and selected cancers
J Jasionowska, P Gałecki, E Kalinka, A Skiba… - Journal of Psychiatric …, 2024 - Elsevier
Altered immune system activity is one of the common pathomechanisms of depressive
disorders and cancer. The aim of this study is to evaluate level of selected elements of the …
disorders and cancer. The aim of this study is to evaluate level of selected elements of the …
[HTML][HTML] Synergistic effects of the combinational use of escitalopram oxalate and 5-fluorouracil on the inhibition of gastric cancer SNU-1 cells
VCH Chen, JY Huang, BS Tzang, TC Hsu… - International Journal of …, 2022 - mdpi.com
Owing to its high recurrence rate, gastric cancer (GC) is the leading cause of tumor-related
deaths worldwide. Besides surgical treatment, chemotherapy is the most commonly used …
deaths worldwide. Besides surgical treatment, chemotherapy is the most commonly used …
Glioma induces atypical depression-like behaviors in mice through the 5-HT and glutamatergic synapse pathways
B Li, K Ran, Z Jing, W Han, X Peng - Biochemical and Biophysical …, 2024 - Elsevier
Glioma patients often undertake psychiatric disorders such as depression and anxiety.
There are several clinical epidemiological studies on glioma-associated depression, but …
There are several clinical epidemiological studies on glioma-associated depression, but …
A Ketogenic Diet Sensitizes Pancreatic Cancer to Inhibition of Glutamine Metabolism
Pancreatic cancer is the third leading cause of cancer death in the United States, and while
conventional chemotherapy remains the standard treatment, responses are poor. Safe and …
conventional chemotherapy remains the standard treatment, responses are poor. Safe and …
Modulation of the Indolamine 2, 3 Dioxygenase Pathway as a Means of Treating Depression
N Ramos, T Ichim, E Lin, F Lin, RV Akana, S Kesari… - 2023 - osf.io
Despite significant progress made in understanding and treatment of Major Depressive
Disorder (MDD), conventional approaches still possess significant shortcomings, supporting …
Disorder (MDD), conventional approaches still possess significant shortcomings, supporting …
Сравнительный анализ содержания триптофана и метаболитов кинуренинового и серотонинового путей у пациентов с артериальной гипертензией и …
МВ Кожевникова, АВ Кривова, ЕО Коробкова… - Кардиология, 2022 - lib.ossn.ru
Аннотация Цель Сравнительный анализ содержания триптофана (Трп) и его
метаболитов в сыворотке крови лиц без сердечно-сосудистых заболеваний (ССЗ) и …
метаболитов в сыворотке крови лиц без сердечно-сосудистых заболеваний (ССЗ) и …