We carried out systematic review and meta-analysis to evaluate whether peripheral levels of
pro-inflammatory markers including Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), Tumor …

In contrast to traditional perspectives of resilience as a stable, trait-like characteristic,
resilience is now recognized as a multidimentional, dynamic capacity influenced by life-long …

Is depression among older adults symptomatically different than younger adults? Is it more
common or chronic or difficult to treat? Is depression in late life more likely to be attributed to …

Mental health and well-being are consistently influenced—directly or indirectly—by multiple
environmental exposures. In this review, we have attempted to address some of the most …

Introduction: Individuals suffering from psychiatric disorders experience high levels of illness
burden and a significantly reduced quality of life. Despite targeted psychopharmacological …

Deficits in cognition, reward processing, and motor function are clinical features relevant to
both aging and depression. Individuals with late-life depression often show impairment …

Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

Depression is a common and disabling comorbidity in rheumatoid arthritis that not only
decreases the likelihood of remission and treatment adherence but also increases the risk of …

Introduction Handgrip strength is a simple and inexpensive marker of health and mortality
risk. It presents an ideal risk-stratifying method for use in low and middle-income countries …

Recent neuroimaging studies have characterized the pathophysiology of late-life depression
(LLD) as a dysfunction of the brain networks involved in the regulation of emotion …