Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain. Over time, different tests and models have been developed in …

Rodent marble-burying behavior in the marble-burying test (MBT) is employed as a model or
measure to study anxiety-and compulsive-like behaviors or anxiolytic and anticompulsive …

The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae …

Object burying by rodents is a popular screening tool for anxiolytic agents. However,
modulation of marble-burying by serotonin reuptake inhibitors prompted its link to obsessive …

Adolescence is a time period in development when the brain undergoes substantial
remodeling in response to the environment. To determine whether a stressful experience …

Marble burying is considered an, albeit controversial, animal model of the compulsive like
behaviors of obsessive-compulsive disorder (OCD). Hallmark features of OCD patients are …

Rationale Obsessive-compulsive disorder (OCD) is characterized by repetitive behaviors
exacerbated by stress. Many OCD patients do not respond to available pharmacotherapies …

The present study evaluated anxiolytic activity of (+)-limonene epoxide (EL), through the
marble burying test (MBT) assay, and the antioxidant potential in vitro and in vivo in mice …

According to the Research Domain Criteria (RDoC), phenotypic differences among
disorders may be explained by variations in the nature and degree of neural circuitry …

OBJECTIVE: To study the influence of methanolic and aqueous extract of Withania
somnifera (W. somnifera) root on the marble-burying behavior of mice a well-accepted …