[HTML][HTML] Determinants and outcomes of mitochondrial dynamics
R Quintana-Cabrera, L Scorrano - Molecular Cell, 2023 - cell.com
Mitochondria are not only central organelles in metabolism and energy conversion but are
also platforms for cellular signaling cascades. Classically, the shape and ultrastructure of …
also platforms for cellular signaling cascades. Classically, the shape and ultrastructure of …
The cell biology of mitochondrial membrane dynamics
M Giacomello, A Pyakurel, C Glytsou… - Nature reviews Molecular …, 2020 - nature.com
Owing to their ability to efficiently generate ATP required to sustain normal cell function,
mitochondria are often considered the 'powerhouses of the cell'. However, our …
mitochondria are often considered the 'powerhouses of the cell'. However, our …
Mitochondrial quality control mechanisms as molecular targets in diabetic heart
X Chang, Y Li, C Cai, F Wu, J He, Y Zhang, J Zhong… - Metabolism, 2022 - Elsevier
Mitochondrial dysfunction has been regarded as a hallmark of diabetic cardiomyopathy. In
addition to their canonical metabolic actions, mitochondria influence various other aspects of …
addition to their canonical metabolic actions, mitochondria influence various other aspects of …
Mitochondrial fusion: the machineries in and out
S Gao, J Hu - Trends in cell biology, 2021 - cell.com
Mitochondria are highly dynamic organelles that constantly undergo fission and fusion.
Disruption of mitochondrial dynamics undermines their function and causes several human …
Disruption of mitochondrial dynamics undermines their function and causes several human …
Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies
Mitochondrial function is vital for normal cellular processes. Mitochondrial damage and
oxidative stress have been greatly implicated in the progression of aging, along with the …
oxidative stress have been greatly implicated in the progression of aging, along with the …
[HTML][HTML] Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology
RG Abrisch, SC Gumbin, BT Wisniewski… - The Journal of cell …, 2020 - ncbi.nlm.nih.gov
The steady-state morphology of the mitochondrial network is maintained by a balance of
constitutive fission and fusion reactions. Disruption of this steady-state morphology results in …
constitutive fission and fusion reactions. Disruption of this steady-state morphology results in …
Mitochondrial dynamics and inheritance during cell division, development and disease
P Mishra, DC Chan - Nature reviews Molecular cell biology, 2014 - nature.com
During cell division, it is critical to properly partition functional sets of organelles to each
daughter cell. The partitioning of mitochondria shares some common features with that of …
daughter cell. The partitioning of mitochondria shares some common features with that of …
Mito-morphosis: mitochondrial fusion, fission, and cristae remodeling as key mediators of cellular function
L Pernas, L Scorrano - Annual review of physiology, 2016 - annualreviews.org
Permanent residency in the eukaryotic cell pressured the prokaryotic mitochondrial ancestor
to strategize for intracellular living. Mitochondria are able to autonomously integrate and …
to strategize for intracellular living. Mitochondria are able to autonomously integrate and …
Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin
T Ban, T Ishihara, H Kohno, S Saita, A Ichimura… - Nature cell …, 2017 - nature.com
Mitochondria are highly dynamic organelles that undergo frequent fusion and fission. Optic
atrophy 1 (OPA1) is an essential GTPase protein for both mitochondrial inner membrane …
atrophy 1 (OPA1) is an essential GTPase protein for both mitochondrial inner membrane …
Mitochondrial fission, fusion, and stress
RJ Youle, AM Van Der Bliek - Science, 2012 - science.org
Mitochondrial fission and fusion play critical roles in maintaining functional mitochondria
when cells experience metabolic or environmental stresses. Fusion helps mitigate stress by …
when cells experience metabolic or environmental stresses. Fusion helps mitigate stress by …