Posture, locomotion, spatial orientation, and motion sickness as a function of space flight
MF Reschke, JJ Bloomberg, DL Harm, WH Paloski… - Brain Research …, 1998 - Elsevier
This article summarizes a variety of newly published findings obtained by the Neuroscience
Laboratory, Johnson Space Center, and attempts to place this work within a historical …
Laboratory, Johnson Space Center, and attempts to place this work within a historical …
The role of GSK-3β in the regulation of protein turnover, myosin phenotype, and oxidative capacity in skeletal muscle under disuse conditions
TM Mirzoev, KA Sharlo, BS Shenkman - International journal of molecular …, 2021 - mdpi.com
Skeletal muscles, being one of the most abundant tissues in the body, are involved in many
vital processes, such as locomotion, posture maintenance, respiration, glucose …
vital processes, such as locomotion, posture maintenance, respiration, glucose …
Alterations of functional brain connectivity after long-duration spaceflight as revealed by fMRI
E Pechenkova, I Nosikova, A Rumshiskaya… - Frontiers in …, 2019 - frontiersin.org
The present study reports alterations of task-based functional brain connectivity in a group of
11 cosmonauts after a long-duration spaceflight, compared to a healthy control group not …
11 cosmonauts after a long-duration spaceflight, compared to a healthy control group not …
Effects of spaceflight on the vestibular system
TK Clark - Handbook of space pharmaceuticals, 2022 - Springer
Here on Earth, the vestibular system provides sensory information to assist with orientation
and motion perception, balance, locomotion, stabilizing eye movements, and various other …
and motion perception, balance, locomotion, stabilizing eye movements, and various other …
Developing proprioceptive countermeasures to mitigate postural and locomotor control deficits after long-duration spaceflight
TR Macaulay, BT Peters, SJ Wood… - Frontiers in Systems …, 2021 - frontiersin.org
Astronauts experience post-flight disturbances in postural and locomotor control due to
sensorimotor adaptations during spaceflight. These alterations may have adverse …
sensorimotor adaptations during spaceflight. These alterations may have adverse …
Effects of various muscle disuse states and countermeasures on muscle molecular signaling
K Sharlo, SA Tyganov, E Tomilovskaya… - International Journal of …, 2021 - mdpi.com
Skeletal muscle is capable of changing its structural parameters, metabolic rate and
functional characteristics within a wide range when adapting to various loading regimens …
functional characteristics within a wide range when adapting to various loading regimens …
Plantar mechanical stimulation prevents calcineurin-NFATc1 inactivation and slow-to-fast fiber type shift in rat soleus muscle under hindlimb unloading
K Sharlo, I Paramonova, O Turtikova… - Journal of Applied …, 2019 - journals.physiology.org
The prevailing myosin isoform [myosin heavy chain (MyHC)] in a skeletal muscle determines
contractile properties of the muscle. Under actual or simulated microgravity conditions such …
contractile properties of the muscle. Under actual or simulated microgravity conditions such …
Plantar mechanical stimulation attenuates protein synthesis decline in disused skeletal muscle via modulation of nitric oxide level
SA Tyganov, E Mochalova, S Belova, K Sharlo… - Scientific Reports, 2021 - nature.com
Both research conducted under microgravity conditions and ground-based space analog
studies have shown that air pump-based plantar mechanical stimulation (PMS) of cutaneous …
studies have shown that air pump-based plantar mechanical stimulation (PMS) of cutaneous …
Sensorimotor reconditioning during and after spaceflight
SJ Wood, JA Loehr, ME Guilliams - NeuroRehabilitation, 2011 - content.iospress.com
Exposure to microgravity drives adaptive changes in healthy individuals reconditioned for
abnormal gravity states. These changes are maladaptive for return to earth's gravity. The …
abnormal gravity states. These changes are maladaptive for return to earth's gravity. The …
Plantar mechanical stimulation maintains slow myosin expression in disused rat soleus muscle via NO-dependent signaling
KA Sharlo, II Paramonova, ID Lvova… - International Journal of …, 2021 - mdpi.com
It was observed that gravitational unloading during space missions and simulated
microgravity in ground-based studies leads to both transformation of slow-twitch muscle …
microgravity in ground-based studies leads to both transformation of slow-twitch muscle …