Analytical and biochemical perspectives of protein O-GlcNAcylation
Protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) is a
unique monosaccharide modification discovered in the early 1980s. With the technological …
unique monosaccharide modification discovered in the early 1980s. With the technological …
Metal-coordination chemistry guiding preferred crystallographic orientation for reversible zinc anode
The long-term reversible plating/stripping of Zn anodes is one of the decisive parts inside
various Zn based aqueous batteries, but originally restricted by irregular dendrite/by …
various Zn based aqueous batteries, but originally restricted by irregular dendrite/by …
Approaches towards understanding the mechanism-of-action of metallodrugs
Known as highly efficient metallodrugs that have been clinically used to treat various types
of cancers, cisplatin and its analogues have attracted and inspired extensive interest in the …
of cancers, cisplatin and its analogues have attracted and inspired extensive interest in the …
A systematic role of metabolomics, metabolic pathways, and chemical metabolism in lung cancer
S Kannampuzha, AG Mukherjee, UR Wanjari… - Vaccines, 2023 - mdpi.com
Lung cancer (LC) is considered as one of the leading causes of cancer-associated
mortalities. Cancer cells' reprogrammed metabolism results in changes in metabolite …
mortalities. Cancer cells' reprogrammed metabolism results in changes in metabolite …
Comparative NMR metabolomics of the responses of A2780 human ovarian cancer cells to clinically established Pt-based drugs
Pt-Based drugs play a very important role in current cancer treatments; yet, their cellular and
mechanistic aspects are not fully understood. NMR metabolomics provides a powerful tool to …
mechanistic aspects are not fully understood. NMR metabolomics provides a powerful tool to …
Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy
W Shao, J Gu, C Huang, D Liu, H Huang, Z Huang… - Molecular cancer, 2014 - Springer
Background Ambiguity in malignant transformation of glioma has made prognostic diagnosis
very challenging. Tumor malignant transformation is closely correlated with specific …
very challenging. Tumor malignant transformation is closely correlated with specific …
Tryptophan pathway-targeted metabolomics study on the mechanism and intervention of cisplatin-induced acute kidney injury in rats
B Tan, J Chen, S Qin, C Liao, Y Zhang… - Chemical Research …, 2021 - ACS Publications
Cisplatin is a chemotherapeutic agent widely employed in the treatment of various solid
tumors. However, its use is often restricted by acute kidney injury (AKI) which is the dose …
tumors. However, its use is often restricted by acute kidney injury (AKI) which is the dose …
NMR-based metabolomics in metal-based drug research
Thanks to recent advances in analytical technologies and statistical capabilities, the
application field of metabolomics has increased significantly. Currently, this approach is …
application field of metabolomics has increased significantly. Currently, this approach is …
1H HR-MAS NMR Based Metabolic Profiling of Cells in Response to Treatment with a Hexacationic Ruthenium Metallaprism as Potential Anticancer Drug
M Vermathen, LEH Paul, G Diserens, P Vermathen… - PLoS …, 2015 - journals.plos.org
1H high resolution magic angle spinning (HR-MAS) NMR spectroscopy was applied in
combination with multivariate statistical analyses to study the metabolic response of whole …
combination with multivariate statistical analyses to study the metabolic response of whole …
Response of osteosarcoma cell metabolism to platinum and palladium chelates as potential new drugs
AS Martins, ALM Batista de Carvalho, MPM Marques… - Molecules, 2021 - mdpi.com
This paper reports the first metabolomics study of the impact of new chelates Pt2Spm and
Pd2Spm (Spm= Spermine) on human osteosarcoma cellular metabolism, compared to the …
Pd2Spm (Spm= Spermine) on human osteosarcoma cellular metabolism, compared to the …