BCL-2 family proteins are the regulators of apoptosis, but also have other functions. This
family of interacting partners includes inhibitors and inducers of cell death. Together they …

Apoptosis is a form of programmed cell death critical for the development and homeostasis
of multicellular organisms. A key event within the mitochondrial pathway to apoptosis is the …

Yeasts, such as Saccharomyces cerevisiae, have long served as useful models for the study
of oxidative stress, an event associated with cell death and severe human pathologies. This …

Two phylogenetically and structurally distinct groups of proteins regulate stress induced
intrinsic apoptosis, the programmed disassembly of cells. Together they form the B cell …

Classical apoptotic cell death is now sufficiently well understood to be interrogated with
mathematical modeling and manipulated with targeted drugs for clinical benefit. However, a …

В монографии изложены современные взгляды на применение проточной
цитофлуориметрии в норме и при различных патологических процессах. Приведена …

In this chapter we discuss methods that can be used to study apoptotic cell death in the
Drosophila embryo, ovary, as well as in cultured cell lines. These methods assay various …

How do cells age and die? For the past 20 years, the budding yeast, Saccharomyces
cerevisiae, has been used as a model organism to uncover the genes that regulate lifespan …

It is now well established that the mitochondrion is a central regulator of mammalian cell
apoptosis. However, the importance of this organelle in non-mammalian apoptosis has long …

Apoptosis and autophagy, the mechanisms of programmed cell death, play critical roles in
physiological and pathological processes in both vertebrates and invertebrates. Apoptosis is …