The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives
S Wang, Y Zheng, F Yang, L Zhu, XQ Zhu… - Signal transduction and …, 2021 - nature.com
Pancreatic cancer is an increasingly common cause of cancer mortality with a tight
correspondence between disease mortality and incidence. Furthermore, it is usually …
correspondence between disease mortality and incidence. Furthermore, it is usually …
Small nucleolar RNAs: insight into their function in cancer
J Liang, J Wen, Z Huang, X Chen, B Zhang… - Frontiers in …, 2019 - frontiersin.org
Small nucleolar RNAs (SnoRNAs) are a class of non-coding RNAs divided into two classes:
C/D box snoRNAs and H/ACA box snoRNAs. The canonical function of C/D box and H/ACA …
C/D box snoRNAs and H/ACA box snoRNAs. The canonical function of C/D box and H/ACA …
Decoding pseudouridine: an emerging target for therapeutic development
Pseudouridine (Ψ) is the most abundant post-transcriptional RNA modification and is
widespread in multiple RNA species. Ψ impacts various aspects of RNA biology, conferring …
widespread in multiple RNA species. Ψ impacts various aspects of RNA biology, conferring …
A pan-cancer analysis of the expression and clinical relevance of small nucleolar RNAs in human cancer
Increasing evidence has demonstrated that small nucleolar RNAs (snoRNAs) play important
roles in tumorigenesis. We systematically investigated the expression landscape and clinical …
roles in tumorigenesis. We systematically investigated the expression landscape and clinical …
Non-coding RNAs and epithelial mesenchymal transition in cancer: molecular mechanisms and clinical implications
H Khanbabaei, S Ebrahimi… - Journal of Experimental …, 2022 - Springer
Epithelial-mesenchymal transition (EMT) is a fundamental process for embryonic
development during which epithelial cells acquire mesenchymal characteristics, and the …
development during which epithelial cells acquire mesenchymal characteristics, and the …
Insulin-like growth factor 1-induced enolase 2 deacetylation by HDAC3 promotes metastasis of pancreatic cancer
Y Zheng, C Wu, J Yang, Y Zhao, H Jia, M Xue… - Signal transduction and …, 2020 - nature.com
Abstract Enolase 2 (ENO2) is a key glycolytic enzyme in the metabolic process of glycolysis,
but its potential function in pancreatic ductal adenocarcinoma (PDAC) is unclear. In this …
but its potential function in pancreatic ductal adenocarcinoma (PDAC) is unclear. In this …
Non-coding small nucleolar RNA SNORD17 promotes the progression of hepatocellular carcinoma through a positive feedback loop upon p53 inactivation
J Liang, G Li, J Liao, Z Huang, J Wen, Y Wang… - Cell Death & …, 2022 - nature.com
Recent evidence suggests that small nucleolar RNAs (snoRNAs) are involved in the
progression of various cancers, but their precise roles in hepatocellular carcinoma (HCC) …
progression of various cancers, but their precise roles in hepatocellular carcinoma (HCC) …
Small extracellular vesicle non-coding RNAs in pancreatic cancer: molecular mechanisms and clinical implications
M Reese, SA Dhayat - Journal of hematology & oncology, 2021 - Springer
Pancreatic cancer has the worst prognosis among common tumors which is attributed to its
aggressive phenotype, diagnosis at advanced, inoperable stages, and resistance to …
aggressive phenotype, diagnosis at advanced, inoperable stages, and resistance to …
p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis
Overexpression of EZH2 in estrogen receptor negative (ER-) breast cancer promotes
metastasis. EZH2 has been mainly studied as the catalytic component of the Polycomb …
metastasis. EZH2 has been mainly studied as the catalytic component of the Polycomb …
SnoRNA in cancer progression, metastasis and immunotherapy response
J van der Werf, CV Chin, NI Fleming - Biology, 2021 - mdpi.com
Simple Summary A much larger number of small nucleolar RNA (snoRNA) have been found
encoded within our genomes than we ever expected to see. The activities of the snoRNAs …
encoded within our genomes than we ever expected to see. The activities of the snoRNAs …