[HTML][HTML] Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

[HTML][HTML] Long COVID or post-COVID-19 condition: past, present and future research directions

C Fernández-de-Las-Peñas, AV Raveendran… - Microorganisms, 2023 - mdpi.com
The presence of symptoms after an acute SARS-CoV-2 infection (long-COVID) has become
a worldwide healthcare emergency but remains underestimated and undertreated due to a …

[HTML][HTML] Increased risk of severe clinical course of COVID-19 in carriers of HLA-C* 04: 01

J Weiner, P Suwalski, M Holtgrewe, A Rakitko… - …, 2021 - thelancet.com
Background Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic,
there has been increasing urgency to identify pathophysiological characteristics leading to …

[HTML][HTML] Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of …

G Godoy-Tena, A Barmada, O Morante-Palacios… - Genome Medicine, 2022 - Springer
Background COVID-19 manifests with a wide spectrum of clinical phenotypes, ranging from
asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are …

[HTML][HTML] Whole blood DNA methylation analysis reveals respiratory environmental traits involved in COVID-19 severity following SARS-CoV-2 infection

G Barturen, E Carnero-Montoro… - Nature …, 2022 - nature.com
SARS-CoV-2 infection can cause an inflammatory syndrome (COVID-19) leading, in many
cases, to bilateral pneumonia, severe dyspnea, and in~ 5% of these, death. DNA …

[HTML][HTML] COVID-19 is a multi-organ aggressor: epigenetic and clinical marks

MM Kgatle, IO Lawal, G Mashabela… - Frontiers in …, 2021 - frontiersin.org
The progression of coronavirus disease 2019 (COVID-19), resulting from a severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, may be influenced by both …

[HTML][HTML] A machine learning approach utilizing DNA methylation as an accurate classifier of COVID-19 disease severity

S Bowler, G Papoutsoglou, A Karanikas… - Scientific Reports, 2022 - nature.com
Since the onset of the COVID-19 pandemic, increasing cases with variable outcomes
continue globally because of variants and despite vaccines and therapies. There is a need …

[HTML][HTML] Longitudinal study of DNA methylation and epigenetic clocks prior to and following test-confirmed COVID-19 and mRNA vaccination

APS Pang, AT Higgins-Chen, F Comite, I Raica… - Frontiers in …, 2022 - frontiersin.org
The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence
suggest that severe COVID-19 is associated with durable scars to the epigenome …

Novel 3D-printed microfluidic magnetic platform for rapid DNA isolation

G Kibar, B Sarıarslan, S Doğanay, G Yıldız… - Analytical …, 2024 - ACS Publications
This study presents a novel miniaturized device as a 3D-printed microfluidic magnetic
platform specifically designed to manipulate magnetic microparticles in a microfluidic chip …

[HTML][HTML] Persistent blood DNA methylation changes one year after SARS-CoV-2 infection

J Balnis, A Madrid, KJ Hogan, LA Drake, A Adhikari… - Clinical …, 2022 - Springer
We recently reported the COVID-19-induced circulating leukocytes DNA methylation profile.
Here, we hypothesized that some of these genes would persist differentially methylated after …