Differentiated sex chromosomes in mammals and other vertebrates evolved independently
but in strikingly similar ways. Vertebrates with differentiated sex chromosomes share the …

Epithelial ovarian cancer (OvCa) is associated with high mortality and, as the majority (>
75%) of women with OvCa have metastatic disease at the time of diagnosis, rates of survival …

高通量测序是核酸测序研究的一次革命性技术创新, 该技术以极低的单碱基测序成本和超高的
数据产出量为特征, 为基因组学和后基因组学研究带来了新的科研方法和解决方案 …

The field of molecular biology is advancing fast with new powerful technologies, sequencing
methods and analysis software being developed constantly. Commonly used tools originally …

Epigenetic inheritance plays a crucial role in many biological processes, such as gene
expression in early embryo development, imprinting and the silencing of transposons. It has …

Epigenetics is defined as the study of changes in gene function that are mitotically or
meiotically heritable and do not lead to a change in DNA sequence. Epigenetic …

DNA methylation refers to the addition of a methyl group to nucleotides within DNA. As with
other epigenetic endpoints, patterns of DNA methylation are susceptible to alterations due to …

Migration is a complex behavioural adaptation for survival that has evolved across the
animal kingdom from invertebrates to mammals. In some taxa, closely related migratory …

DNA methylation (DNAm) is a key mechanism for regulating gene expression in animals
and levels are known to change with age. Recent studies have used DNAm changes as a …

DNA methylation is a key epigenetic modification in the vertebrate genomes known to be
involved in biological processes such as regulation of gene expression, DNA structure and …