Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …

Autoimmune diseases affect roughly 5-10% of the total population, with women affected
more than men. The standard treatment for autoimmune or autoinflammatory diseases had …

Current therapies for autoimmune diseases, such as multiple sclerosis (MS), induce broad
suppression of the immune system, potentially promoting opportunistic infections. Here, we …

Poly (lactic-co-glycolic acid)(PLGA) particles are a widely used and extensively studied drug
delivery system. The favorable properties of PLGA such as good bioavailability, controlled …

Tolerogenic vaccines are aimed at inhibiting antigen-specific immune responses. Antigen-
loaded nanoparticles (NPs) have been recently emerged as ideal tools for tolerogenic …

It is difficult to carry out early diagnosis and treatment of Multiple sclerosis (MS) because of
the complex pathogenesis elicited by diversified autoantigens. Monocytes play important …

Autoimmune disease is a chronic inflammatory disease caused by disorders of immune
regulation. Antigen-specific immunotherapy has the potential to inhibit the autoreactivity of …

The immune system maintains homeostasis and protects the body from pathogens, mutated
cells, and other harmful substances. When immune homeostasis is disrupted, excessive …

The intravenous delivery of disease-relevant antigens (Ag) by polymeric nanoparticles (NP-
Ags) has demonstrated Ag-specific immune tolerance in autoimmune and allergic disorders …

Autoimmune diseases, such as celiac disease, multiple sclerosis, and type 1 diabetes, are
leading causes of morbidity and mortality in the United States. In these disease states …