Intratumoral immunotherapy: from trial design to clinical practice

S Champiat, L Tselikas, S Farhane, T Raoult… - Clinical Cancer …, 2021 - AACR
Systemic immunotherapies such as immune checkpoint blockade targeted at PD (L) 1 and
CTLA4 have demonstrated their ability to provide durable tumor responses and long-term …

Abscopal effect in radioimmunotherapy

M Ashrafizadeh, B Farhood, AE Musa, S Taeb… - International …, 2020 - Elsevier
Abscopal effect is an interesting phenomenon in radiobiology that causes activation of
immune system against cancer cells. Traditionally, this phenomenon was known as a …

Stress management in plants: examining provisional and unique dose-dependent responses

M Georgieva, V Vassileva - International Journal of Molecular Sciences, 2023 - mdpi.com
The purpose of this review is to critically evaluate the effects of different stress factors on
higher plants, with particular attention given to the typical and unique dose-dependent …

The interactions and communications in tumor resistance to radiotherapy: Therapy perspectives

M Ashrafizadeh, B Farhood, AE Musa, S Taeb… - International …, 2020 - Elsevier
Tumor microenvironment (TME) includes a wide range of cell types including cancer cells,
cells which are involved in stromal structure and immune cells (tumor suppressor and tumor …

Anti-tumor effects of exosomes derived from drug-incubated permanently growing human MSC

C Melzer, J Ohe, R Hass - International Journal of Molecular Sciences, 2020 - mdpi.com
Similar to growth-limited human primary cultures of mesenchymal stroma/stem-like cells
(MSC), the continuously proliferating human MSC544 cell line produced extracellular …

An engineered Prussian blue nanoparticles‐based nanoimmunotherapy elicits robust and persistent immunological memory in a TH‐MYCN neuroblastoma model

A Shukla, J Cano-Mejia, J Andricovich… - Advanced …, 2021 - Wiley Online Library
A combination therapy using Prussian blue nanoparticles (PBNP) as photothermal therapy
(PTT) agents coated with CpG oligodeoxynucleotides, an immunologic adjuvant, as a …

Highlighting the potential for chronic stress to minimize therapeutic responses to radiotherapy through increased immunosuppression and radiation resistance

M Chen, AK Singh, EA Repasky - Cancers, 2020 - mdpi.com
Simple Summary Stress is an integral part of life and is necessary for proper development
and function of every organ. However, there is growing evidence that prolonged activation of …

Physical modulation of mesenchymal stem cell exosomes: A new perspective for regenerative medicine

D Wu, X Zhao, J Xie, R Yuan, Y Li, Q Yang… - Cell …, 2024 - Wiley Online Library
Mesenchymal stem cell‐derived exosomes (MSC‐Exo) offer promising therapeutic potential
for various refractory diseases, presenting a novel therapeutic strategy. However, their …

Exosomes participate in the radiotherapy resistance of cancers

D He, Z Zhao, B Fu, X Li, L Zhao, Y Chen… - Radiation …, 2022 - meridian.allenpress.com
Radiotherapy is one of the main treatment modalities for cancer. However, some cancer
patients will gradually develop resistance to radiotherapy, leading to tumor recurrence and …

Rationale for the use of radiation-activated mesenchymal stromal/stem cells in acute respiratory distress syndrome

I Tovar, R Guerrero, JJ López-Peñalver, J Expósito… - Cells, 2020 - mdpi.com
We have previously shown that the combination of radiotherapy with human umbilical-cord-
derived mesenchymal stromal/stem cells (MSCs) cell therapy significantly reduces the size …