Collagen, the most abundant extracellular matrix protein in animal kingdom belongs to a
family of fibrous proteins, which transfer load in tissues and which provide a highly …

Valvular heart diseases (VHDs) are currently treated using either mechanical or
bioprosthetic heart valves. Unfortunately, mechanical valves require lifelong anticoagulation …

Decellularized extracellular matrix (dECM) is a promising biomaterial for repairing
cardiovascular tissue, as dECM most effectively captures the complex array of proteins …

Transplantation is the only curative treatment option available for patients suffering from end‐
stage organ failure, improving their quality of life and long‐term survival. However, because …

Cardiovascular disease is the leading cause of death in the developed world, and as such
there is a pressing need for treatment options. Cardiac tissue engineering emerged from the …

Regenerative medicine and tissue engineering strategies have made remarkable progress
in remodeling, replacing, and regenerating damaged cardiovascular tissues. The design of …

A variety of decellularized materials have been developed that have demonstrated potential
for treating cardiovascular diseases and improving our understanding of cardiac …

Cardiovascular disease (CVD) is one of the leading causes of death in the Western world.
The replacement of damaged vessels and valves has been practiced since the 1950's …

Naturally-derived biomaterials have been used for decades in multiple regenerative
medicine applications. From the simplest cell microcarriers made of collagen or alginate, to …

Decellularized extracellular matrix (dECM) derived from myocardium has been widely
explored as a nature scaffold for cardiac tissue engineering applications. Cardiac dECM …