When ischemic stroke occurs, oxygen and energy depletion triggers a cascade of events,
including inflammatory responses, glutamate excitotoxicity, oxidative stress, and apoptosis …

Introduction Immunotherapies for multiple sclerosis (MS) significantly decrease the risk of
new relapses. However, the chronic compartmentalized inflammation and …

Oxidative stress within the arthritis joint has been indicated to be involved in generating
mediators for tissue degeneration and inflammation. COX-2 is a mediator in inflammatory …

This study was conducted to investigate the effects of pyrroloquinoline quinone disodium
(PQQ· Na 2) on inflammatory responses, oxidative stress, and intestinal morphology of …

ABSTRACT PQQ has anti-inflammatory and anti-oxidant effects. PQQ can relieve high
glucose-induced renal cell damage by suppressing Keap1 expression. Keap1 can interact …

Phytomedicine based natural flavonoids have potent antioxidant, anti-inflammatory, and
neuroprotective activities against neurodegenerative diseases. The aim of the present study …

Multi-year crewed space exploration missions are now on the horizon; therefore, it is
important that we understand and mitigate the physiological effects of spaceflight. The …

Neuroinflammation triggered by activation of glial cells plays an important role in the
pathophysiology of several neurodegenerative diseases including Parkinson's disease …

Important functions of intestinal epithelial cells (IECs) include enabling nutrient absorption to
occur passively and acting as a defense barrier against potential xenobiotic components …

Neuroinflammation is a feature common to neurodegenerative diseases, such as
Parkinson's disease (PD), which might be responsive to therapeutic intervention. Rotenone …