Multiparametric MRI (mpMRI) is an imaging modality that combines anatomical MR imaging
with one or more functional MRI sequences. It has become a versatile tool for detecting and …

Rigorous validation with ground truth information such as histology is needed to reliably
assess the current and potential value of MRI techniques to characterize tissue and identify …

Purpose To assess the underlying genomic variation of prostate gland microenvironments of
patients with prostate adenocarcinoma in the context of colocalized multiparametric …

As the development of modalities for prostate cancer (PCa) imaging advances, the
challenge of accurate registration between images and histopathologic ground truth …

Abstract Objective Magnetic Resonance Imaging (MRI) of the prostate provides useful in
vivo diagnostic tissue information such as tumor location and aggressiveness, but ex vivo …

PURPOSE Spatial heterogeneity of tumors is a major challenge in precision oncology. The
relationship between molecular and imaging heterogeneity is still poorly understood …

Background Microvascular invasion (MVI) is an independent risk factor for postoperative
recurrence of hepatocellular carcinoma (HCC). However, MVI cannot be detected by …

Despite tremendous advancements in in vivo imaging modalities, there remains substantial
uncertainty with respect to tumor delineation on in these images. Histopathology remains the …

Registration of histopathology volumes to Magnetic Resonance Images (MRI) is a crucial
step for finding correlations in Prostate Cancer (PCa) and assessing tumor agressivity. This …

Spatial intratumoural heterogeneity is a major challenge in precision medicine. Progress to
better understand the relationship between genetic heterogeneity and tissue heterogeneity …