[HTML][HTML] Exploring the journey of emodin as a potential neuroprotective agent: novel therapeutic insights with molecular mechanism of action
Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants,
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …
The biology and pathobiology of glutamatergic, cholinergic, and dopaminergic signaling in the aging brain
A Gasiorowska, M Wydrych, P Drapich… - Frontiers in aging …, 2021 - frontiersin.org
The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …
implications. Clinical and experimental studies on aging have uncovered numerous …
Therapeutic potential of natural products in treating neurodegenerative disorders and their future prospects and challenges
Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …
extensively studied in recent years for their therapeutic potential in a variety of …
[HTML][HTML] CRISPR/Cas9 genome editing for neurodegenerative diseases
JN Nojadeh, NSB Eryilmaz, Bİ Ergüder - EXCLI journal, 2023 - ncbi.nlm.nih.gov
Gene therapy has emerged as a promising therapeutic strategy for various conditions,
including blood disorders, ocular disease, cancer, and nervous system disorders. The …
including blood disorders, ocular disease, cancer, and nervous system disorders. The …
telemedicine during and beyond COVID-19
Telemedicine has been at the mainstay of patient care by offsetting the decline in outpatient
visits during the Coronavirus disease 2019 (COVID-19) while providing critical patient …
visits during the Coronavirus disease 2019 (COVID-19) while providing critical patient …
CRISPR-Cas9-based technology and its relevance to gene editing in Parkinson's disease
Parkinson's disease (PD) and other chronic and debilitating neurodegenerative diseases
(NDs) impose a substantial medical, emotional, and financial burden on individuals and …
(NDs) impose a substantial medical, emotional, and financial burden on individuals and …
Phase separation and pathologic transitions of RNP condensates in neurons: implications for amyotrophic lateral sclerosis, frontotemporal dementia and other …
Liquid–liquid phase separation results in the formation of dynamic biomolecular
condensates, also known as membrane-less organelles, that allow for the assembly of …
condensates, also known as membrane-less organelles, that allow for the assembly of …
Virtual reality as a technological-aided solution to support communication in persons with neurodegenerative diseases and acquired brain injury during COVID-19 …
F Stasolla, M Matamala-Gomez, S Bernini… - Frontiers in Public …, 2021 - frontiersin.org
The COVID-19 poses an ongoing threat to lives around the world and challenges the
existing public health and medical service delivery. The lockdown or quarantine measures …
existing public health and medical service delivery. The lockdown or quarantine measures …
Contribution of autophagy-lysosomal pathway in the exosomal secretion of alpha-synuclein and its impact in the progression of Parkinson's disease
D Sepúlveda, M Cisternas-Olmedo, J Arcos… - Frontiers in Molecular …, 2022 - frontiersin.org
Parkinson's disease (PD) is caused by the degeneration of dopaminergic neurons due to an
accumulation of intraneuronal abnormal alpha-synuclein (α-syn) protein aggregates. It has …
accumulation of intraneuronal abnormal alpha-synuclein (α-syn) protein aggregates. It has …
Symmetric subgenomes and balanced homoeolog expression stabilize the establishment of allopolyploidy in cyprinid fish
L Ren, X Gao, J Cui, C Zhang, H Dai, M Luo, S He… - BMC biology, 2022 - Springer
Background Interspecific postzygotic reproduction isolation results from large genetic
divergence between the subgenomes of established hybrids. Polyploidization immediately …
divergence between the subgenomes of established hybrids. Polyploidization immediately …