Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …

The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …

Hypervalent iodine (III) compounds have found wide application in modern organic
chemistry as environmentally friendly reagents and catalysts. Hypervalent iodine reagents …

The utility of carbazole in photo-, electro-, and medicinal applications has ensured its
widespread use also as the backbone in tridentate pincer ligands. In this review, the aim is …

This tutorial review highlights key principles underpinning the design of selected
metallodrugs to target specific biological macromolecules (DNA and proteins). The review …

Aiming to design economical metal-based medications to replace platinum-based drugs in
the treatment of a variety of cancers, this article presents four new Zn (II) and Cd (II) …

Three ruthenium (III) complexes with pyrazolopyrimidine [Ru (Ln)(H2O) Cl3](1–3, n= 1–3)
were prepared and characterized. These Ru (III) compounds show strong cytotoxicity …

Au (III) bis (pyrrolide-imine) chelates are emerging as a class of versatile, efficacious
metallodrug candidates. Here, we synthesised two enantiopure chiral ligands H2L1 and …

The ability of gold-based complexes in diagnosis and treatment of cancers as the main
worldwide health problems, along with the successful clinical reports of bioactive azole …