Leveraging crosslinking mass spectrometry in structural and cell biology
A Graziadei, J Rappsilber - Structure, 2022 - cell.com
Crosslinking mass spectrometry (crosslinking-MS) is a versatile tool providing structural
insights into protein conformation and protein-protein interactions. Its medium-resolution …
insights into protein conformation and protein-protein interactions. Its medium-resolution …
Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes
Structural maintenance of chromosomes (SMC) complexes are essential for chromatin
organization and functions throughout the cell cycle. The cohesin and condensin SMCs fold …
organization and functions throughout the cell cycle. The cohesin and condensin SMCs fold …
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
The exploration of protein structure and function stands at the forefront of life science and
represents an ever‐expanding focus in the development of proteomics. As mass …
represents an ever‐expanding focus in the development of proteomics. As mass …
[HTML][HTML] xiVIEW: Visualisation of crosslinking mass spectrometry data
CW Combe, M Graham, L Kolbowski, L Fischer… - Journal of Molecular …, 2024 - Elsevier
Crosslinking mass spectrometry (MS) has emerged as an important technique for
elucidating the in-solution structures of protein complexes and the topology of protein …
elucidating the in-solution structures of protein complexes and the topology of protein …
Molecular structure of soluble vimentin tetramers
Intermediate filaments (IFs) are essential constituents of the metazoan cytoskeleton. A vast
family of cytoplasmic IF proteins are capable of self-assembly from soluble tetrameric …
family of cytoplasmic IF proteins are capable of self-assembly from soluble tetrameric …
Molecular architecture of the augmin complex
Accurate segregation of chromosomes during mitosis depends on the correct assembly of
the mitotic spindle, a bipolar structure composed mainly of microtubules. The augmin …
the mitotic spindle, a bipolar structure composed mainly of microtubules. The augmin …
The LIKE SEX FOUR 1–malate dehydrogenase complex functions as a scaffold to recruit β-amylase to promote starch degradation
In plant leaves, starch is composed of glucan polymers that accumulate in chloroplasts as
the products of photosynthesis during the day; starch is mobilized at night to continuously …
the products of photosynthesis during the day; starch is mobilized at night to continuously …
Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding
Correct folding of outer membrane proteins (OMPs) into the outer membrane of Gram-
negative bacteria depends on delivery of unfolded OMPs to the β-barrel assembly …
negative bacteria depends on delivery of unfolded OMPs to the β-barrel assembly …
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity
Abstract Tudor Interacting Repair Regulator (TIRR) is an RNA-binding protein (RBP) that
interacts directly with 53BP1, restricting its access to DNA double-strand breaks (DSBs) and …
interacts directly with 53BP1, restricting its access to DNA double-strand breaks (DSBs) and …
Effects of vegetation cover and aquaculture pollution on viral assemblages in mangroves sediments
Y Su, H Yu, C Gao, S Sun, Y Liang, G Liu… - Journal of Hazardous …, 2024 - Elsevier
Mangrove forests, a critical coastal ecosystem, face numerous anthropogenic threats,
particularly from aquaculture activities. Despite the acknowledged significance of viruses in …
particularly from aquaculture activities. Despite the acknowledged significance of viruses in …