Circular RNAs: biogenesis, function and role in human diseases
Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
MicroRNA therapeutics in cancer: current advances and challenges
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
BNPMDA: bipartite network projection for MiRNA–disease association prediction
Motivation A large number of resources have been devoted to exploring the associations
between microRNAs (miRNAs) and diseases in the recent years. However, the experimental …
between microRNAs (miRNAs) and diseases in the recent years. However, the experimental …
Biogenesis, functions and clinical significance of circRNAs in gastric cancer
C Shan, Y Zhang, X Hao, J Gao, X Chen, K Wang - Molecular cancer, 2019 - Springer
Gastric cancer (GC) is one of the most common malignant tumours in the world and has high
morbidity and mortality. Circular RNAs (circRNAs) are a class of non-coding RNAs with …
morbidity and mortality. Circular RNAs (circRNAs) are a class of non-coding RNAs with …
[HTML][HTML] EGF receptor ligands: recent advances
B Singh, G Carpenter, RJ Coffey - F1000Research, 2016 - ncbi.nlm.nih.gov
Seven ligands bind to and activate the mammalian epidermal growth factor (EGF) receptor
(EGFR/ERBB1/HER1): EGF, transforming growth factor-alpha (TGFA), heparin-binding EGF …
(EGFR/ERBB1/HER1): EGF, transforming growth factor-alpha (TGFA), heparin-binding EGF …
Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of oral cancer
Oral cancer (OC) is a widely observed neoplasm on a global scale. Over time, there has
been an increase in both its fatality and incidence rates. Oral cancer metastasis is a complex …
been an increase in both its fatality and incidence rates. Oral cancer metastasis is a complex …
[PDF][PDF] A microRNA‐7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib‐resistant cells in human hepatocellular carcinoma
TD Kabir, C Ganda, RM Brown, DJ Beveridge… - …, 2018 - Wiley Online Library
Sorafenib remains the only approved drug for treating patients with advanced hepatocellular
carcinoma (HCC). However, the therapeutic effect of sorafenib is transient, and patients …
carcinoma (HCC). However, the therapeutic effect of sorafenib is transient, and patients …
Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib
Elevated expression and activity of the epidermal growth factor receptor (EGFR) is
associated with development and progression of head and neck cancer (HNC) and a poor …
associated with development and progression of head and neck cancer (HNC) and a poor …
Effect of the size and shape of dendronized iron oxide nanoparticles bearing a targeting ligand on MRI, magnetic hyperthermia, and photothermia properties—from …
B Freis, MDLA Ramirez, C Kiefer, S Harlepp, C Iacovita… - Pharmaceutics, 2023 - mdpi.com
Functionalized iron oxide nanoparticles (IONPs) are increasingly being designed as a
theranostic nanoplatform combining specific targeting, diagnosis by magnetic resonance …
theranostic nanoplatform combining specific targeting, diagnosis by magnetic resonance …
microRNA-7: a tumor suppressor miRNA with therapeutic potential
FC Kalinowski, RAM Brown, C Ganda, KM Giles… - The international journal …, 2014 - Elsevier
Abstract microRNAs are a family of endogenous, short, non-coding RNAs that play critical
roles in regulating gene expression for key cellular processes in normal and abnormal …
roles in regulating gene expression for key cellular processes in normal and abnormal …