Healthy effects of plant polyphenols: molecular mechanisms

M Leri, M Scuto, ML Ontario, V Calabrese… - International journal of …, 2020 - mdpi.com
The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …

Health Effects of Phenolic Compounds Found in Extra-Virgin Olive Oil, By-Products, and Leaf of Olea europaea L.

A Romani, F Ieri, S Urciuoli, A Noce, G Marrone… - Nutrients, 2019 - mdpi.com
Olea europaea L. fruit is a peculiar vegetal matrix containing high levels of fatty acids (98–
99% of the total weight of extra-virgin olive oil, EVOO) and low quantities (1–2%) of …

Implications of peptide assemblies in amyloid diseases

PC Ke, MA Sani, F Ding, A Kakinen, I Javed… - Chemical Society …, 2017 - pubs.rsc.org
Neurodegenerative disorders and type 2 diabetes are global epidemics compromising the
quality of life of millions worldwide, with profound social and economic implications. Despite …

Bioactivity of olive oil phenols in neuroprotection

C Angeloni, M Malaguti, MC Barbalace… - International Journal of …, 2017 - mdpi.com
Neurological disorders such as stroke, Alzheimer's and Parkinson's diseases are associated
with high morbidity and mortality, and few or no effective options are available for their …

Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans

S Rigacci, M Stefani - International journal of molecular sciences, 2016 - mdpi.com
The increasing interest in the Mediterranean diet hinges on its healthy and anti-ageing
properties. The composition of fatty acids, vitamins and polyphenols in olive oil, a key …

Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases

C Nediani, J Ruzzolini, A Romani, L Calorini - Antioxidants, 2019 - mdpi.com
Growing scientific literature data suggest that the intake of natural bioactive compounds
plays a critical role in preventing or reducing the occurrence of human chronic non …

Interactions between antidiabetic drugs and herbs: an overview of mechanisms of action and clinical implications

RC Gupta, D Chang, S Nammi, A Bensoussan… - Diabetology & metabolic …, 2017 - Springer
Diabetes is a complex condition with a variety of causes and pathophysiologies. The current
single target approach has not provided ideal clinical outcomes for the treatment of the …

Potential role of olive oil phenolic compounds in the prevention of neurodegenerative diseases

J Rodríguez-Morató, L Xicota, M Fitó, M Farré… - Molecules, 2015 - mdpi.com
Adherence to the Mediterranean Diet (MD) has been associated with a reduced incidence of
neurodegenerative diseases and better cognitive performance. Virgin olive oil, the main …

Natural product-based amyloid inhibitors

P Velander, L Wu, F Henderson, S Zhang… - Biochemical …, 2017 - Elsevier
Many chronic human diseases, including multiple neurodegenerative diseases, are
associated with deleterious protein aggregates, also called protein amyloids. One common …

Targeting amyloid aggregation: an overview of strategies and mechanisms

S Giorgetti, C Greco, P Tortora, FA Aprile - International journal of …, 2018 - mdpi.com
Amyloids result from the aggregation of a set of diverse proteins, due to either specific
mutations or promoting intra-or extra-cellular conditions. Structurally, they are rich in …