From tyrosine to melanin: Signaling pathways and factors regulating melanogenesis

Z Rzepka, E Buszman, A Beberok… - Advances in Hygiene and …, 2016 - phmd.pl
Melanins are natural pigments of skin, hair and eyes and can be classified into two main
types: brown to black eumelanin and yellow to reddish-brown pheomelanin. Biosynthesis of …

Implications of melanin binding in ocular drug delivery

AK Rimpelä, M Reinisalo, L Hellinen… - Advanced drug delivery …, 2018 - Elsevier
Pigmented ocular tissues contain melanin within the intracellular melanosomes. Drugs bind
to melanin at varying extent that ranges from no binding to extensive binding. Binding may …

Phosphorus-modified copper ferrite (P–CuFe2O4) nanoparticles for photocatalytic ozonation of lomefloxacin

HS Jarusheh, S Al Jitan, F Banat, MA Haija… - Chemosphere, 2023 - Elsevier
Phosphorus-modified copper ferrite (P–CuFe 2 O 4) nanoparticles were prepared by a
simple sol-gel auto-combustion process and used for the photocatalytic ozonation of …

Gold-palladium nanoparticles aided electrochemically reduced graphene oxide sensor for the simultaneous estimation of lomefloxacin and amoxicillin

N Kumar, RN Goyal - Sensors and Actuators B: Chemical, 2017 - Elsevier
A gold-palladium nanoparticles decorated electrochemically reduced graphene oxide
(AuNP-PdNP-ErGO) modified, glassy carbon sensor has been developed for the individual …

Construction of UiO-66@ MoS2 flower-like hybrids through electrostatically induced self-assembly with enhanced photodegradation activity towards lomefloxacin

D Gao, Y Zhang, H Yan, B Li, Y He, P Song… - Separation and …, 2021 - Elsevier
Although metal organic frameworks (MOFs) presented excellent photocatalytic activities, the
rapid recombination of light-induced charges and low visible light utilization efficiency …

Design and evaluation of proniosomes as a carrier for ocular delivery of lomefloxacin HCl

RM Khalil, GA Abdelbary, M Basha… - Journal of liposome …, 2017 - Taylor & Francis
The current investigation aims to develop and evaluate novel ocular proniosomal gels of
lomefloxacin HCl (LXN); in order to improve its ocular bioavailability for the management of …

Enhancement of lomefloxacin Hcl ocular efficacy via niosomal encapsulation: in vitro characterization and in vivo evaluation

RM Khalil, GA Abdelbary, M Basha… - Journal of liposome …, 2017 - Taylor & Francis
The aim of this study is to develop and evaluate niosomal dispersions loaded with the
hydrophilic drug; lomefloxacin Hcl (LXN) for the management of ocular bacterial …

A novel electrochemical sensor based on molecularly imprinted polymer with binary functional monomers at Fe-doped porous carbon decorated Au electrode for the …

J Li, X Huang, J Ma, S Wei, H Zhang - Ionics, 2020 - Springer
A novel molecularly imprinted polymer (MIP) electrochemical sensor for the sensitive
detection of lomefloxacin (LFX) was developed for the first time. For this, Fe-doped porous …

Ciprofloxacin-mediated induction of S-phase cell cycle arrest and apoptosis in COLO829 melanoma cells

A Beberok, D Wrześniok, A Minecka, J Rok… - Pharmacological …, 2018 - Elsevier
Background Low effectiveness of anti-melanoma therapies makes it necessary to search for
new drugs that could improve or replace the standard chemotherapy. Fluoroquinolones are …

[HTML][HTML] Molecular and biochemical basis of fluoroquinolones-induced phototoxicity—The study of antioxidant system in human melanocytes exposed to UV-A …

J Kowalska, K Banach, J Rok, A Beberok… - International Journal of …, 2020 - mdpi.com
Phototoxicity of fluoroquinolones is connected with oxidative stress induction. Lomefloxacin
(8-halogenated derivative) is considered the most phototoxic fluoroquinolone and …