Doxorubicin (DOX), is a very effective chemotherapeutic agent against cancer whose clinical
use is limited by toxicity. Different strategies have been proposed to attenuate toxicity …

Anthracyclines (doxorubicin, daunorubicin, epirubicin, and idarubicin) are currently the most
effective group of anti-neoplastic drugs used in clinical practice. Of these, doxorubicin (also …

The oxidative injury of renal tubular epithelial cells caused by inflammation and oxidative
stress induced by hyperoxaluria is an important factor in the kidney calcium oxalate (CaOx) …

Crystal modulators play a significant role in the formation of calcium oxalate stone disease.
When renal cells are subjected to oxalate stress, the loss in cell integrity leads to exposure …

AKI remains a major public health concern. Despite years of investigation, no intervention
has been demonstrated to reliably prevent AKI in humans. Thus, development of novel …

The diabetes mellitus (DM) induces several changes, with substantial increase of reactive
oxygen species (ROS). The ROS cause damage to systemic and renal microvasculature …

Although doxorubicin (DOX) is a commonly used chemotherapeutic agent its clinical use is
restricted due to its organ toxicities. The present investigation relates to reducing DOX …

Iron accumulation is associated with the pathophysiology of chronic kidney disease (CKD).
Renal fibrosis is a final common feature that contributes to the progression of CKD; however …

Background Though resveratrol is known to have anti-cancer, anti-diabetic, anti-oxidant and
anti-inflammatory activities, the inhibitory mechanism of resveratrol in kidney stone formation …

The aims of our study were to evaluate the antioxidant defence mechanisms of liver tissue
challenged by doxorubucin (DOX) and to compare the possible protective effects of N …