Lipotoxicity: The missing link between diabetes and periodontitis?

Y Sun, Y Yin, S Yang, D Ai, H Qin, X Xia… - Journal of …, 2024 - Wiley Online Library
Lipotoxicity refers to the accumulation of lipids in tissues other than adipose tissue (body fat).
It is one of the major pathophysiological mechanisms responsible for the progression of …

Effects of Natural Products through Inhibiting Endoplasmic Reticulum Stress on Attenuation of Idiopathic Pulmonary Fibrosis

JL Deng, J Liu, WS Chen, Q Liang, YQ He… - Drug Design …, 2024 - Taylor & Francis
With ever-increasing intensive studies of idiopathic pulmonary fibrosis (IPF), significant
progresses have been made. Endoplasmic reticulum stress (ERS)/unfolded protein reaction …

[HTML][HTML] EMC10 modulates hepatic ER stress and steatosis in an isoform specific manner

K Chen, Y Wang, J Yang, N Klöting, C Liu, J Dai… - Journal of …, 2024 - Elsevier
Background & aims Endoplasmic reticulum (ER) membrane protein complex subunit 10
(EMC10) has been implicated in obesity. Here we investigated the roles of the two isoforms …

Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis …

Q Song, CL Hwang, Y Li, J Wang, J Park, SM Lee… - Metabolism, 2024 - Elsevier
Background & aims Dysbiosis contributes to alcohol-associated liver disease (ALD);
however, the precise mechanisms remain elusive. Given the critical role of the gut …