Lanthipeptides are ribosomally synthesized and post-translationally modified peptides
(RiPPs) that display a wide variety of biological activities, from antimicrobial to antiallodynic …

Lantibiotics are believed to have a conceivable potential to be used as therapeutics,
especially against clinically resistant bacterial strains. However, their low solubility and poor …

The rise of antibiotic resistance demands the acceleration of molecular diversification
strategies to inspire new chemical entities for antibiotic medicines. We report here on the …

A novel lanC-like sequence was identified from the dominant human gut bacterium Blautia
obeum strain A2-162. This sequence was extended to reveal a putative lantibiotic operon …

The secretion of peptides and proteins is essential for survival and ecological adaptation of
bacteria. Dual-functional ATP-binding cassette transporters export antimicrobial or quorum …

Lanthipeptides belong to the family of ribosomally synthesized and post-translationally
modified peptides (RiPPs). The (methyl) lanthionine cross-links characteristic to …

Lanthipeptides are ribosomally synthesized and post-translationally modified peptides that
are generated from precursor peptides through a dehydration and cyclization process …

Natural bioactive peptide discovery is a challenging and time-consuming process. However,
advances in synthetic biology are providing promising new avenues in peptide engineering …

Lanthipeptides are a representative class of RiPPs that possess characteristic lanthionine
and/or methyllanthionine thioether cross-links. The biosynthetic potentials of marine-derived …

Lanthipeptides are ribosomally synthesized and post-translationally modified peptides
characterized by the presence of lanthionine rings that provide stability and functionality …