Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature

IJ Onakpoya, CJ Heneghan, JK Aronson - BMC medicine, 2016 - Springer
Background There have been no studies of the patterns of post-marketing withdrawals of
medicinal products to which adverse reactions have been attributed. We identified medicinal …

Factors associated with underreporting of adverse drug reactions by health care professionals: a systematic review update

P García-Abeijon, C Costa, M Taracido, MT Herdeiro… - Drug Safety, 2023 - Springer
Introduction Underreporting is a major limitation of the voluntary reporting system of adverse
drug reactions (ADRs). A 2009 systematic review showed the knowledge and attitudes of …

Pharmacovigilance in low‐and middle‐income countries: a review with particular focus on Africa

R Kiguba, S Olsson, C Waitt - British journal of clinical …, 2023 - Wiley Online Library
Low‐and middle‐income countries (LMIC) face unique challenges with regard to the
establishment of robust pharmacovigilance systems capable of generating data to inform …

Adverse drug reaction reporting in Africa and a comparison of individual case safety report characteristics between Africa and the rest of the world: analyses of …

HH Ampadu, J Hoekman, ML de Bruin, SN Pal… - Drug safety, 2016 - Springer
Introduction Following the start of the World Health Organization (WHO) Programme for
International Drug Monitoring (PIDM) by 10 member countries in 1968, it took another 24 …

Incidence, risk factors and risk prediction of hospital-acquired suspected adverse drug reactions: a prospective cohort of Ugandan inpatients

R Kiguba, C Karamagi, SM Bird - BMJ open, 2017 - bmjopen.bmj.com
Objectives To determine the incidence and risk factors of hospital-acquired suspected
adverse drug reactions (ADRs) among Ugandan inpatients. We also constructed risk scores …

Educational intervention to improve the knowledge, attitude and practice of healthcare professionals regarding pharmacovigilance in South-South Nigeria

AO Opadeyi, A Fourrier-Réglat… - Therapeutic advances in …, 2019 - journals.sagepub.com
Background: Our aim in this study was to evaluate the effect of a combined educational
intervention and year-long monthly text message reinforcements via the Short Messaging …

Facilitators and barriers to uptake of the med safety mobile app for adverse drug reaction reporting by health workers in Uganda: a qualitative study

R Kiguba, H Zakumumpa, HB Ndagije, N Mwebaza… - Drug Safety, 2023 - Springer
Abstract Introduction Adverse drug reactions (ADRs) are an important public health
challenge worldwide; however, pharmacovigilance systems are plagued by under-reporting …

Predicting the need for third-line antiretroviral therapy by identifying patients at high risk for failing second-line antiretroviral therapy in South Africa

D Onoya, C Nattey, E Budgell… - AIDS patient care and …, 2017 - liebertpub.com
Although third-line antiretroviral therapy (ART) is available in South Africa's public sector, its
cost is substantially higher than first and second line. Identifying risk factors for failure on …

Adverse drug reactions among patients initiating second-line antiretroviral therapy in South Africa

D Onoya, K Hirasen, L van den Berg, J Miot, LC Long… - Drug Safety, 2018 - Springer
Introduction Understanding the occurrence of antiretroviral (ARV)-related adverse events
(AEs) among patients receiving second-line antiretroviral therapy (ART) is important in …

Barriers to the success of an electronic pharmacovigilance reporting system in Kenya: an evaluation three years post implementation

OO Agoro, SW Kibira, JV Freeman… - Journal of the American …, 2018 - academic.oup.com
Objective Electronic pharmacovigilance reporting systems are being implemented in many
developing countries in an effort to improve reporting rates. This study sought to establish …