[HTML][HTML] Pharmacokinetics and target attainment of antibiotics in critically ill children: a systematic review of current literature

SJF Hartman, RJ Brüggemann, L Orriëns, N Dia… - Clinical …, 2020 - Springer
Background Pharmacokinetics (PK) are severely altered in critically ill patients due to
changes in volume of distribution (Vd) and/or drug clearance (Cl). This affects the target …

[HTML][HTML] Determinants of misuse of antibiotics among parents of children attending clinics in regional referral hospitals in Tanzania

RF Mutagonda, AI Marealle, L Nkinda, U Kibwana… - Scientific reports, 2022 - nature.com
Parents are the important implementers on appropriate/inappropriate use of antibiotics,
especially in the pediatric population. Limited studies have associated poor knowledge …

[HTML][HTML] Impact of pharmacist-led antibiotic stewardship program in a PICU of low/middle-income country

A Haque, K Hussain, R Ibrahim, Q Abbas… - BMJ open …, 2018 - bmjopenquality.bmj.com
Objective To assess the effect of implementation of pharmacist-led customised ASP and to
compare with historical control on usage of antibiotics as well as COT in our PICU. Methods …

Antibiotic indications and appropriateness in the pediatric intensive care unit: a 10-center point prevalence study

K Chiotos, J Blumenthal, J Boguniewicz… - Clinical Infectious …, 2023 - academic.oup.com
Background Antibiotics are prescribed to most pediatric intensive care unit (PICU) patients,
but data describing indications and appropriateness of antibiotic orders in this population …

International survey on determinants of antibiotic duration and discontinuation in pediatric critically ill patients

KC Noël, J Papenburg, J Lacroix, C Quach… - Pediatric Critical Care …, 2020 - journals.lww.com
Objectives: We hypothesized that antibiotic use in PICUs is based on criteria not always
supported by evidence. We aimed to describe determinants of empiric antibiotic use in …

[HTML][HTML] Prevalence and risk factors associated with drug resistant bacteria in neonatal and pediatric intensive care units: A retrospective study in Saudi Arabia

AS Bazaid, A Aldarhami, NA Bokhary, MB Bazaid… - Medicine, 2023 - journals.lww.com
Successful empirical antibiotic therapy for infected patients with multi drug resistant bacteria
(MDR) can be challenging task in various healthcare settings, including neonatal and …

Evaluasi Penggunaan Antibiotik Secara Kualitatif dan Analisis Efektivitas Biaya pada Pasien Pediatri di RSUP Fatmawati Jakarta

F Kristiani, M Radji, A Rianti - JSFK (Jurnal Sains Farmasi …, 2019 - jsfk.ffarmasi.unand.ac.id
Peresepan antibiotika yang tidak tepat akan meningkatkan kejadian resistensi. Resistensi
antimikroba telah menjadi masalah kesehatan yang mendunia dengan dampak …

[HTML][HTML] Steady-state pharmacokinetics of vancomycin in children admitted to pediatric intensive care unit of a tertiary referral center

NB Mali, MS Tullu, PP Wandalkar… - Indian Journal of …, 2019 - ncbi.nlm.nih.gov
Aims and objectives Vancomycin is a drug of choice for various gram-positive bacterial
(GPB) infections and is largely prescribed to pediatric intensive care unit (PICU) patients …

[HTML][HTML] A prospective antibacterial utilization study in pediatric intensive care unit of a tertiary referral center

NB Mali, SP Deshpande, MS Tullu… - Indian Journal of …, 2018 - ncbi.nlm.nih.gov
Purpose: Antibacterials are commonly prescribed to Pediatric Intensive Care Unit (PICU)
patients. However, inappropriate antibacterial prescriptions lead to increases in antibacterial …

[HTML][HTML] Evaluating antimicrobial appropriateness in a tertiary care pediatric ICU in Saudi Arabia: a retrospective cohort study

YM Kazzaz, H AlTurki, L Aleisa, B Alahmadi… - … Resistance & Infection …, 2020 - Springer
Background Inappropriate antibiotic utilization is associated with the emergence of
antimicrobial resistance (AMR) and a decline in antibiotic susceptibility in many pathogenic …