Current cancer nanomedicines can only mitigate adverse effects but fail to enhance
therapeutic efficacies of anticancer drugs. Rational design of next‐generation cancer …

Reduction-sensitive biodegradable polymers and conjugates have emerged as a
fascinating class of biomedical materials that can be elegantly applied for intracellular …

Self-amplifying RNA (saRNA) vaccines are highly advantageous, as they result in enhanced
protein expression compared to mRNA (mRNA), thus minimizing the required dose …

A series of novel bioreducible poly (amido amine) s containing multiple disulfide linkages
(SS-PAAs) were synthesized and evaluated as nonviral gene vectors. These linear SS-PAAs …

Here a novel photo, pH, and redox triple-responsive nanogel of poly (acrylic acid-co-
spiropyran methacrylate) crosslinked by disulfide-containing N, N-bis (acryloyl) cystamine …

Poly (amido ethylenimine) polymers, a new type of peptidomimetic polymer, containing
multiple disulfide bonds (SS-PAEIs) designed to degrade after delivery of plasmid DNA …

Polymers that depolymerize by a cascade of intramolecular reactions in response to the
removal of a stabilizing end-cap can allow for an unprecedented degree of control over the …

In recent years, numerous delivery systems based on polymers, dendrimers, and nano-scale
assemblies have been developed to improve the properties of drug molecules. In general …

Disassemblable micelles for intracellular delivery of doxorubicin were developed based on
a reduction-degradable amphiphilic polyamide amine-g-polyethylene glycol graft copolymer …

In this work, a facile click reaction strategy is employed to form hydrogels in situ with
cytocompatibility, biodegradability, self-healing property and resistance to protein. The thiol …