Peptide-based drugs have garnered considerable attention in recent years owing to their
increasingly crucial role in the treatment of diverse diseases. However, the limited …

The term “peptoids” was introduced decades ago to describe peptide analogues that exhibit
better physicochemical and pharmacokinetic properties than peptides. Oligo (N-substituted …

This study presents a Pd (II)-catalyzed method for the β-C (sp3)–H arylation of N-Cbz-or N-
Fmoc-protected N-methyl alanines, providing ready access to building blocks for N …

Enzymatically degradable peptides are commonly used as linkers within hydrogels for
biological applications; however, controlling the degradation of these engineered peptides …

Proteases, especially MMPs, are attractive biomarkers given their central role in both
physiological and pathological processes. Distinguishing MMP activity with degradable …

Dipeptides 1 and 2 were synthesized from unnatural amino acids containing pyrene as a
fluorescent label and polynucleotide binding unit, and modified tyrosine as a …

An efficient conversion of hydroxyproline “customizable” units into new amino acids with a
variety of N-alkyl substituents is described. The process is versatile and can afford valuable …

Statins are essential naturally occurring β-hydroxy-γ-amino acids and (3S, 4S)-Statine,
derived from L-Leucine, is found in important aspartic proteases inhibitors like Pepstatin A …

The development of Alzheimer's disease (AD), the most prevalent form of dementia, is
associated with the abnormal aggregation of Amyloid-β (Aβ) peptides into fibrils and …

Oligo (N─ substituted glycine)(oligo─ NSG), also known as peptoid, is a synthetic oligomer
with high proteolytic stability and membrane permeability due to the N─ substituted …