Cyclic dipeptides: Biological activities and self‐assembled materials

K Zhao, R Xing, X Yan - Peptide Science, 2021 - Wiley Online Library
Cyclic dipeptides (CDPs) are the smallest cyclic peptides containing 2, 5‐diketopiperazine
rings. CDPs have advantages of structures and properties, including excellent hydrogen …

Complex regulatory networks of virulence factors in Vibrio vulnificus

G Choi, SH Choi - Trends in Microbiology, 2022 - cell.com
The fulminating zoonotic pathogen Vibrio vulnificus is the causative agent of fatal septicemia
in humans and fish, raising tremendous economic burdens in healthcare and the …

Quorum sensing and iron-dependent coordinated control of autoinducer-2 production via small RNA RyhB in Vibrio vulnificus

KW Lee, Y Wen, NY Park, KS Kim - Scientific Reports, 2022 - nature.com
Roles for the non-coding small RNA RyhB in quorum-sensing and iron-dependent gene
modulation in the human pathogen V. vulnificus were assessed in this study. Both the …

Independent promoter recognition by TcpP precedes cooperative promoter activation by TcpP and ToxR

AL Calkins, LM Demey, JD Karslake, ED Donarski… - MBio, 2021 - Am Soc Microbiol
Cholera is a diarrheal disease caused by the Gram-negative bacterium Vibrio cholerae. To
reach the surface of intestinal epithelial cells, proliferate, and cause disease, V. cholerae …

NhaR, LeuO, and H-NS Are Part of an Expanded Regulatory Network for Ectoine Biosynthesis Expression

KE Boas Lichty, GJ Gregory… - Applied and Environmental …, 2023 - Am Soc Microbiol
Bacteria accumulate compatible solutes to maintain cellular turgor pressure when exposed
to high salinity. In the marine halophile Vibrio parahaemolyticus, the compatible solute …

Effect of capsular polysaccharide phase variation on biofilm formation, motility and gene expression in Vibrio vulnificus

T Zhang, S Ji, M Zhang, F Wu, X Li, X Luo, Q Huang… - Gut Pathogens, 2024 - Springer
Vibrio vulnificus, a significant marine pathogen, undergoes opaque (Op)-translucent (Tr)
colony switching based on whether capsular polysaccharide (CPS) is produced. CPS phase …

Iron-Fur complex suppresses the expression of components of the cyclo-(Phe-Pro)-signaling regulatory pathway in Vibrio vulnificus

KW Lee, S Kim, S Lee, M Kim, S Song… - Frontiers in …, 2023 - frontiersin.org
In the human pathogen Vibrio vulnificus, the quorum-sensing (QS) signal molecule cyclo-(L-
phenylalanine-L-proline)(cFP) plays a critical role in triggering a signaling pathway involving …

[HTML][HTML] H-NS silences gene expression of LeuO, the master regulator of the cyclic (Phe-Pro)-dependent signal pathway, in Vibrio vulnificus

NY Park, KW Lee, KS Kim - Journal of Microbiology and …, 2020 - ncbi.nlm.nih.gov
The histone-like nucleoid structuring protein (H-NS) is an abundant global regulator of
environmentally controlled gene expression. Herein, we demonstrate that H-NS represses …

Cyclo(Phe-Pro) produced by Vibrio species passes through biological membranes by simple diffusion

NY Park, YB Cho, OB Kim, KS Kim - Applied Microbiology and …, 2020 - Springer
Abstract Cyclo (Phe-Pro)(cFP), produced by the Vibrio species, plays the dual roles of being
a signaling molecule and a virulence factor. Acting modes of this compound have recently …

LeuO and H-NS are part of an expanded regulatory network for ectoine biosynthesis expression

K Boas Lichty, GJ Gregory, EF Boyd - bioRxiv, 2022 - biorxiv.org
Bacteria accumulate compatible solutes, to maintain cellular turgor pressure when exposed
to high salinity. In the marine halophile Vibrio parahaemolyticus, the compatible solute …