High-throughput proteomics and AI for cancer biomarker discovery

Q Xiao, F Zhang, L Xu, L Yue, OL Kon, Y Zhu… - Advanced drug delivery …, 2021 - Elsevier
Biomarkers are assayed to assess biological and pathological status. Recent advances in
high-throughput proteomic technology provide opportunities for developing next generation …

Evolution of mass spectrometry instruments and techniques for blood proteomics

Y Zhao, Q Xue, M Wang, B Meng, Y Jiang… - Journal of Proteome …, 2023 - ACS Publications
Mass spectrometry (MS)-based blood proteomics is a crucial research focus in identifying
disease biomarkers. Blood serum or plasma is the most commonly used sample for such …

Computational optimization of spectral library size improves DIA-MS proteome coverage and applications to 15 tumors

W Ge, X Liang, F Zhang, Y Hu, L Xu… - Journal of Proteome …, 2021 - ACS Publications
Efficient peptide and protein identifications from data-independent acquisition mass
spectrometric (DIA-MS) data typically rely on a project-specific spectral library with a suitable …

ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets

T Zhu, H Chen, X Yan, Z Wu, X Zhou, Q Xiao… - …, 2021 - academic.oup.com
The rapid progresses of high-throughput sequencing technology-based omics and mass
spectrometry-based proteomics, such as data-independent acquisition and its penetration to …

各种组学分析在体表慢性难愈合创面中的研究进展

曾帅丹, 杨磊 - 中华烧伤与创面修复杂志, 2023 - zhsszz.xml-journal.net
体表慢性难愈合创面的诊断和治疗一直充满着挑战, 对医疗和社会造成巨大负担.
利用高通量测序技术结合组学分析可以揭示慢性创面形成的潜在机制, 识别与慢性创面诊断 …

Phenotype classification using proteome data in a data-independent acquisition tensor format

F Zhang, S Yu, L Wu, Z Zang, X Yi, J Zhu… - Journal of the …, 2020 - ACS Publications
A novel approach for phenotype prediction is developed for data-independent acquisition
(DIA) mass spectrometric (MS) data without the need for peptide precursor identification …

[PDF][PDF] 人工智能结合蛋白质组学研究进展及其在主动脉夹层研究中的展望

吴志石, 马孝琛, 马鹏程, 杨雷, 王瑶婕, 张伟杰, 阿俊… - 临床外科杂志, 2023 - lcwkzz.com
作者单位: 200433 上海, 中国人民解放军海军军医大学第一附属医院血管外科(吴志石, 马孝琛,
马鹏程, 冯家?), 宁夏回族自治区人民医院心脏大血管外科(杨雷, 王瑶婕, 张伟杰), 西湖大学(阿俊 …

Optimization of spectral library size improves DIA-MS proteome coverage

W Ge, X Liang, F Zhang, L Xu, N Xiang, R Sun, W Liu… - bioRxiv, 2020 - biorxiv.org
Efficient peptide and protein identification from data-independent acquisition mass
spectrometric (DIA-MS) data typically rely on an experiment-specific spectral library with a …

Research advances of various omics analyses in chronic refractory wounds on body surface

SD Zeng, L Yang - Zhonghua Shao Shang za zhi= Zhonghua …, 2023 - europepmc.org
The diagnosis and treatment of chronic refractory wounds on body surface has always been
full of challenges, and it also poses a huge burden on medical care and society. High …

[引用][C] Computational proteomics: focus on deep learning

B Wen, B Zhang - Proteomics, 2020 - Wiley Online Library
Proteins are responsible for nearly all cellular functions in living organisms. The
advancements in mass spectrometry (MS)-based proteomics enable high-throughput …