Advantages and disadvantages of inclisiran: a small interfering ribonucleic acid molecule targeting PCSK9—a narrative review
I Merćep, N Friščić, D Strikić… - Cardiovascular …, 2022 - Wiley Online Library
As dyslipidemias remain one of the main risk factors for developing cardiovascular disease,
the question of maintaining optimal lipid levels with pharmacotherapy remains a subject of …
the question of maintaining optimal lipid levels with pharmacotherapy remains a subject of …
Statin non-adherence and residual cardiovascular risk: there is need for substantial improvement
Although statin therapy has proven to be the cornerstone for prevention and treatment of
cardiovascular disease (CVD), there are many patients for whom long-term therapy remains …
cardiovascular disease (CVD), there are many patients for whom long-term therapy remains …
Management of dyslipidaemia in patients with coronary heart disease: results from the ESC-EORP EUROASPIRE V survey in 27 countries
Background and aims One of the objectives of the ESC-EORP EUROASPIRE V survey is to
determine how well European guidelines on the management of dyslipidaemias are …
determine how well European guidelines on the management of dyslipidaemias are …
Evolocumab for early reduction of LDL cholesterol levels in patients with acute coronary syndromes (EVOPACS)
KC Koskinas, S Windecker, G Pedrazzini… - Journal of the American …, 2019 - jacc.org
Background: Although guidelines recommend in-hospital initiation of high-intensity statin
therapy in patients with acute coronary syndromes (ACS), low-density lipoprotein cholesterol …
therapy in patients with acute coronary syndromes (ACS), low-density lipoprotein cholesterol …
[HTML][HTML] Lipid-lowering therapy use in primary and secondary care in Central and Eastern Europe: DA VINCI observational study
M Vrablik, B Seifert, A Parkhomenko, M Banach… - Atherosclerosis, 2021 - Elsevier
Background and aims Central and Eastern Europe (CEE) is a largely understudied region,
despite having the highest cardiovascular disease mortality in Europe. This analysis aimed …
despite having the highest cardiovascular disease mortality in Europe. This analysis aimed …
Achievement of low-density lipoprotein cholesterol goals in 18 countries outside Western Europe: The International ChoLesterol management Practice Study (ICLPS)
N Danchin, W Almahmeed… - European journal of …, 2018 - journals.sagepub.com
Background Little is known about the achievement of low density lipoprotein cholesterol
(LDL-C) targets in patients at cardiovascular risk receiving stable lipid-lowering therapy …
(LDL-C) targets in patients at cardiovascular risk receiving stable lipid-lowering therapy …
Cholesterol target value attainment and lipid-lowering therapy in patients with stable or acute coronary heart disease: results from the Dyslipidemia International Study …
AK Gitt, D Lautsch, J Ferrières, GM De Ferrari, A Vyas… - Atherosclerosis, 2017 - Elsevier
Background and aims Low-density lipoprotein cholesterol (LDL-C) is a major contributor to
cardiovascular disease. In the Dyslipidemia International Study II (DYSIS II), we determined …
cardiovascular disease. In the Dyslipidemia International Study II (DYSIS II), we determined …
Inclisiran lowers LDL-C and PCSK9 irrespective of diabetes status: the ORION-1 randomized clinical trial
OBJECTIVE To evaluate the efficacy and safety of inclisiran by diabetes status. RESEARCH
DESIGN AND METHODS ORION-1 (ClinicalTrials. gov, NCT02597127) randomized 501 …
DESIGN AND METHODS ORION-1 (ClinicalTrials. gov, NCT02597127) randomized 501 …
Medical Therapy for Long-Term Prevention of Atherothrombosis Following an Acute Coronary Syndrome: JACC State-of-the-Art Review
G Gallone, L Baldetti, M Pagnesi, A Latib… - Journal of the American …, 2018 - jacc.org
Following an acute coronary syndrome (ACS), heightened predisposition to
atherothrombotic events may persist for years. Advances in understanding the pathobiology …
atherothrombotic events may persist for years. Advances in understanding the pathobiology …
European Society of Cardiology/European Atherosclerosis Society Task Force consensus statement on proprotein convertase subtilisin/kexin type 9 inhibitors …
U Landmesser, M John Chapman… - European heart …, 2017 - academic.oup.com
Atherosclerotic cardiovascular disease (ASCVD) underlies the thrombotic events intimately
associated with myocardial infarction, a significant proportion of ischaemic strokes, as well …
associated with myocardial infarction, a significant proportion of ischaemic strokes, as well …