Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …
they are of immense importance not only both biologically and industrially but also to the …
Spectroscopic (FT–IR, FT–Raman, UV–Vis) analysis, conformational, HOMO-LUMO, NBO and NLO calculations on monomeric and dimeric structures of 4 …
A Eşme, SG Sağdınç - Journal of Molecular Structure, 2017 - Elsevier
In this study, the Fourier transform infrared (FT–IR) and Fourier transform Raman (FT–
Raman) spectra of 4–pyridazinecarboxylic acid (4PCA) in solid phase were recorded and …
Raman) spectra of 4–pyridazinecarboxylic acid (4PCA) in solid phase were recorded and …
Synthesis and analgesic and anti-inflammatory activities 6-substituted-3 (2H)-pyridazinone-2-acetyl-2-(p-substituted/nonsubstituted benzal) hydrazone derivatives
In this study new 6-substituted-3 (2H)-pyridazinone-2-acetyl-2-(p-substituted benzal)
hydrazone V derivatives were synthesized as analgesic and anti-inflammatory agents. The …
hydrazone V derivatives were synthesized as analgesic and anti-inflammatory agents. The …
Pyridazinone: an important element of pharmacophore possessing broad spectrum of activity
S Dubey, PA Bhosle - Medicinal Chemistry Research, 2015 - Springer
In the last few years, the pyridazine derivatives have been found to exhibit a wide range of
pharmacological activities. A large number of research articles and patents described them …
pharmacological activities. A large number of research articles and patents described them …
Synthesis and structure-activity relationship of some new thiophene-based heterocycles as potential antimicrobial agents
Several new pyrazole, pyridine,[1, 2, 4] triazolo [1, 5-α] pyrimidine, benzimidazo [1, 2-a]
pyrimidine and 1, 2, 4-triazolo [3, 4-c][1, 2, 4] triazine derivatives incorporating a thiophene …
pyrimidine and 1, 2, 4-triazolo [3, 4-c][1, 2, 4] triazine derivatives incorporating a thiophene …
Pyridazin-3(2H)-ones: the versatile pharmacophore of medicinal significance
R Bansal, S Thota - Medicinal Chemistry Research, 2013 - Springer
Abstract Pyridazin-3 (2 H)-one derivatives have attracted the attention of medicinal chemists
during the last decade due to their diverse pharmacological activities. Easy functionalization …
during the last decade due to their diverse pharmacological activities. Easy functionalization …
Synthesis of New 2‐[1 (2H)‐Phthalazinon‐2‐yl] acetamide and 3‐[1 (2H)‐Phthalazinon‐2‐yl] propanamide Derivatives as Antinociceptive and Anti‐inflammatory …
DS Dogruer, E Kupeli, E Yesilada… - Archiv der Pharmazie …, 2004 - Wiley Online Library
As a consequence of our ongoing studies on heterocyclic compounds for new
antinociceptive and anti‐inflammatory agents bearing lactam functional group, new 2‐[1 …
antinociceptive and anti‐inflammatory agents bearing lactam functional group, new 2‐[1 …
Synthesis, analgesic, and anti-inflammatory activities of [6-(3, 5-dimethyl-4-chloropyrazole-1-yl)-3 (2H)-pyridazinon-2-yl] acetamides
M Süküroglu, BÇ Ergün, S ünlü, MF Sahin… - Archives of pharmacal …, 2005 - Springer
A series of structurally diverse amide derivatives of [6-(3, 5-dimethyl-4-chloro-pyrazole-1-yl)-
3 (2H)-pyridazinone-2-yl] acetic acid were prepared and tested for their in vivo analgesic …
3 (2H)-pyridazinone-2-yl] acetic acid were prepared and tested for their in vivo analgesic …
Pyridazinone: an attractive lead for anti-inflammatory and analgesic drug discovery
In spite of the availability of a large number of anti-inflammatory and analgesic agents,
fighting pain and inflammation remains a common problem. The current review article …
fighting pain and inflammation remains a common problem. The current review article …
Synthesis and analgesic and anti-inflammatory activity of new pyridazinones
DS DOĞRUER, MF ŞAHİN, E Küpeli… - Turkish Journal of …, 2003 - journals.tubitak.gov.tr
Abstract A new series of 2-(6-oxo-3, 5-diphenyl-6H-pyridazin-1-yl)-acetamides and 3-[6-oxo-
3, 5-diphenyl-6H-pyridazin-1-yl)-propanamides were synthesized and evaluated in terms of …
3, 5-diphenyl-6H-pyridazin-1-yl)-propanamides were synthesized and evaluated in terms of …