Blue-light receptors for optogenetics

A Losi, KH Gardner, A Möglich - Chemical reviews, 2018 - ACS Publications
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …

Glutamate uptake

NC Danbolt - Progress in neurobiology, 2001 - Elsevier
Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to
glutamate transporter proteins present in the plasma membranes of both glial cells and …

Mitochondrial DNA stress primes the antiviral innate immune response

P West - Biophysical Journal, 2015 - cell.com
Mitochondria are central participants in a variety of cellular processes including ATP
generation, programmed cell death, signal transduction, and innate immunity …

[HTML][HTML] Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis in mice

JB Case, PW Rothlauf, RE Chen, NM Kafai, JM Fox… - Cell host & …, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
human infections, and an effective vaccine is critical to mitigate coronavirus-induced disease …

Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling

JB Eaglesham, Y Pan, TS Kupper, PJ Kranzusch - Nature, 2019 - nature.com
Cytosolic DNA triggers innate immune responses through the activation of cyclic GMP–AMP
synthase (cGAS) and production of the cyclic dinucleotide second messenger 2′, 3′-cyclic …

DNMT1-interacting RNAs block gene-specific DNA methylation

A Di Ruscio, AK Ebralidze, T Benoukraf, G Amabile… - Nature, 2013 - nature.com
DNA methylation was first described almost a century ago; however, the rules governing its
establishment and maintenance remain elusive. Here we present data demonstrating that …

[HTML][HTML] Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2

JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao… - Cell host & …, 2020 - cell.com
Antibody-based interventions against SARS-CoV-2 could limit morbidity, mortality, and
possibly transmission. An anticipated correlate of such countermeasures is the level of …

Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication

I Romero-Brey, A Merz, A Chiramel, JY Lee… - PLoS …, 2012 - journals.plos.org
All positive strand RNA viruses are known to replicate their genomes in close association
with intracellular membranes. In case of the hepatitis C virus (HCV), a member of the family …

HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor

Y Feng, CC Broder, PE Kennedy, EA Berger - Science, 1996 - science.org
A cofactor for HIV-1 (human immunodeficiency virus-type 1) fusion and entry was identified
with the use of a novel functional complementary DNA (cDNA) cloning strategy. This protein …

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

V Lohmann, F Korner, JO Koch, U Herian, L Theilmann… - Science, 1999 - science.org
An estimated 170 million persons worldwide are infected with hepatitis C virus (HCV), a
major cause of chronic liver disease. Despite increasing knowledge of genome structure …