Diversity-Orientated Synthesis and Biological Properties of Compounds Based on the N-Phenylquinoneimine Scaffold

A Adesina, R Skouta - Molecules, 2024 - mdpi.com
The N-phenylquinoneimine scaffold is a versatile synthetic platform that has gained
significant attention in the field of drug discovery due to its structural diversity and capacity to …

Cu‐Catalyzed Chan–Evans–Lam Coupling Reactions of 2‐Nitroimidazole with Aryl Boronic Acids: An Effort toward New Bioactive Agents against S. pneumoniae

S Raju, PE Sheridan, AK Hauer… - Chemistry & …, 2022 - Wiley Online Library
The coupling of phenylboronic acids with poorly‐activated imidazoles is studied as a model
system to explore the use of copper‐catalyzed Chan–Evans–Lam (CEL) coupling for …

Cu−NHC Complex for Chan‐Evans‐Lam Cross‐Coupling Reactions of N‐Heterocyclic Compounds and Arylboronic Acids

B Adhikari, M Teimouri, JW Akin, S Raju… - European Journal of …, 2023 - Wiley Online Library
An efficient copper (II) N‐heterocyclic carbene (NHC) complex with an NCN coordination
mode was optimized to catalyze the Chan–Evans‐Lam (CEL) cross‐coupling reaction of …

Exploiting Iminoquinones as Electrophilic at Nitrogen “N+” Synthons for C–N Bond Construction

LM Mori-Quiroz, CG Comadoll, JE Super… - Organic Letters, 2021 - ACS Publications
New methods for C–N bond construction exploiting the N-centered electrophilic character of
iminoquinones are reported. Iminoquinones, generated in situ via the condensation of o …

Cu‐Catalyzed Cross‐Coupling Reactions of Enamines and Terminal Alkynes: Access of Propargylamines as Neurodegenerative Disorder Agents

L Mohan, JE Lee, M Srinivasarao… - Asian Journal of …, 2023 - Wiley Online Library
Reactions between enamine analogues and terminal alkynes were explored. Copper (I)
complex of 1, 10‐phenanthroline catalyzed these reactions to generate a diastereoselective …

Photocatalytic Annulation of Enaminones with Thioureas for the Synthesis of 2-Aminothiazoles via Tandem C–S and C–N Bond Formation

Q Huang, C Wan, JP Wan - Synthesis, 2024 - thieme-connect.com
Visible-light photocatalytic reactions between enaminones and thioureas leading to thiazole
products have been achieved. The annulation process consists of tandem C–S and C–N …

Radical aminoalkylation of maleimides with alkylamines and alkanes

J Li, W Zhang, YA Li, G Wu… - Applied Organometallic …, 2023 - Wiley Online Library
A meaningful copper‐catalyzed chemo‐selective oxidative alkylamination of maleimides
with secondary alkyl amines and simple alkanes has been developed. This transformation …

Sodium Trifluoroacetate mediated Copper-Catalyzed aza-Michael addition of α, β-unsaturated olefins with aromatic amines

SE Masaeli, M Teimouri, B Adhikari, M Attarroshan… - Tetrahedron letters, 2023 - Elsevier
We present a sodium trifluoroacetate (CF 3 CO 2 Na) mediated copper-catalyzed aza-
Michael addition of aromatic amines with activated olefins under mild, aqueous reaction …

Palladium-Catalyzed N-Alkenylation of N-Aryl Phosphoramidates with Alkenes

YA Li, G Wu, J Li - Molecules, 2023 - mdpi.com
Versatile and concise Pd-catalyzed oxidative N-alkenylation of N-aryl phosphoramidates
with alkenes is described in this study, a reaction that is of great significance but surprisingly …

Synthetic approach to 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides based on common β-keto amide precursors

Y Mollova-Sapundzhieva, P Angelov… - Beilstein Journal of …, 2023 - beilstein-journals.org
Abstract β-Keto amides were used as convenient precursors to both 2-alkyl-4-quinolones
and 2-alkyl-4-quinolone-3-carboxamides. The utility of this approach is demonstrated with …