Dysregulated host response to infection, which cause life‐threatening organ dysfunction,
was defined as sepsis. Sepsis can cause acute and long‐term brain dysfunction, namely …

Sepsis-associated encephalopathy (SAE) is a cognitive impairment associated with sepsis
that occurs in the absence of direct infection in the central nervous system or structural brain …

Sepsis-associated encephalopathy (SAE) is one of the common serious complications in
sepsis, and the pathogenesis of SAE remains unclear. Sirtuin 1 (SIRT1) has been reported …

Sepsis is a leading cause of intensive care unit admission and death worldwide. Most
surviving patients show acute or chronic mental disorders, which are known as sepsis …

Engineered variants of recombinant adeno-associated viruses (rAAVs) are being developed
rapidly to meet the need for gene-therapy delivery vehicles with particular cell-type and …

Molecular pathways mediating systemic inflammation entering the brain parenchyma to
induce sepsis-associated encephalopathy (SAE) remain elusive. Here, we report that in …

Vascular cognitive impairment and dementia (VCID) is the second most common form of
dementia after Alzheimer's disease (AD). Currently, the mechanistic insights into the …

Clinical studies have shown that dexmedetomidine (DEX) reduces mortality and
inflammation in patients with sepsis, and ameliorates cognitive decline in both postoperative …

Encephalopathy of prematurity (EoP) affects approximately 30% of infants born< 32 weeks
gestation and is highly associated with inflammation in the foetus. Here we evaluated the …

Sepsis-associated encephalopathy (SAE) is a neurological complication of sepsis,
characterized by brain dysfunction without any direct central nervous system infection. The …