Prevalence and disease burden of chronic kidney disease
JC Lv, LX Zhang - Renal fibrosis: mechanisms and therapies, 2019 - Springer
Chronic kidney disease (CKD) has been recognized as a leading public health problem
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …
[HTML][HTML] Extracellular vesicles in kidney disease
C Grange, B Bussolati - Nature Reviews Nephrology, 2022 - nature.com
Extracellular vesicles are released by the majority of cell types and circulate in body fluids.
They function as a long-distance cell-to-cell communication mechanism that modulates the …
They function as a long-distance cell-to-cell communication mechanism that modulates the …
[HTML][HTML] Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases
A Ståhl, K Johansson, M Mossberg, R Kahn… - Pediatric …, 2019 - Springer
Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …
Induced pluripotent stem cell (iPSC)–derived extracellular vesicles are safer and more effective for cardiac repair than iPSCs
M Adamiak, G Cheng, S Bobis-Wozowicz… - Circulation …, 2018 - Am Heart Assoc
Rationale: Extracellular vesicles (EVs) are tiny membrane-enclosed droplets released by
cells through membrane budding or exocytosis. The myocardial reparative abilities of EVs …
cells through membrane budding or exocytosis. The myocardial reparative abilities of EVs …
AKI: an increasingly recognized risk factor for CKD development and progression
JT Kurzhagen, S Dellepiane, V Cantaluppi… - Journal of …, 2020 - Springer
Acute kidney injury (AKI) is an increasing health burden with high morbidity and mortality
rates worldwide. AKI is a risk factor for chronic kidney disease (CKD) development and …
rates worldwide. AKI is a risk factor for chronic kidney disease (CKD) development and …
Extracellular vesicles: evolving factors in stem cell biology
Stem cells are proposed to continuously secrete trophic factors that potentially serve as
mediators of autocrine and paracrine activities, associated with reprogramming of the tumor …
mediators of autocrine and paracrine activities, associated with reprogramming of the tumor …
Extracellular vesicles in diagnosis and therapy of kidney diseases
W Zhang, X Zhou, H Zhang, Q Yao… - American Journal of …, 2016 - journals.physiology.org
Extracellular vesicles (EV) are endogenously produced, membrane-bound vesicles that
contain various molecules. Depending on their size and origins, EVs are classified into …
contain various molecules. Depending on their size and origins, EVs are classified into …
[HTML][HTML] Detrimental cross-talk between sepsis and acute kidney injury: new pathogenic mechanisms, early biomarkers and targeted therapies
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency medicine 2016. Other selected articles can be found online at http://www …
Emergency medicine 2016. Other selected articles can be found online at http://www …
[HTML][HTML] Exosomes as drug delivery systems: endogenous nanovehicles for treatment of systemic lupus erythematosus
A Ortega, O Martinez-Arroyo, MJ Forner, R Cortes - Pharmaceutics, 2021 - mdpi.com
Exosomes, nanometer-sized lipid-bilayer-enclosed extracellular vesicles (EVs), have
attracted increasing attention due to their inherent ability to shuttle proteins, lipids and genes …
attracted increasing attention due to their inherent ability to shuttle proteins, lipids and genes …
[HTML][HTML] Extracellular vesicles as mediators of cellular crosstalk between immune system and kidney graft
M Quaglia, S Dellepiane, G Guglielmetti… - Frontiers in …, 2020 - frontiersin.org
Extracellular vesicles (EVs) are known immune-modulators exerting a critical role in kidney
transplantation (KT). EV bioactive cargo includes graft antigens, costimulatory/inhibitory …
transplantation (KT). EV bioactive cargo includes graft antigens, costimulatory/inhibitory …