Major depressive disorder (MDD) is a debilitating neuropsychological disorder, which has
caused serious health and socio-economic burdens worldwide. A growing body of evidence …

Validated measures of animal affect are crucial to research spanning numerous disciplines.
Judgement bias, which assesses decision-making under ambiguity, is a promising measure …

Mood disorders can be considered among the most common and debilitating mental
disorders. Major depression, as an example of mood disorders, is known to severely reduce …

Major depressive disorder (MDD) is a considerable public health concern, which affects
patients worldwide. MDD is associated with psychosocial impairment, poor quality of life …

Animal models in neuropsychiatric research need validation. One way to address external
validity is systematic reviews and meta-analyses. The present study presents a meta …

Bipolar disorder (BD) is a severe and multifactorial disease, with onset usually in young
adulthood, which follows a progressive course throughout life. Replicated epidemiological …

A particular challenge in the development of a bipolar disorder (BD) model in animals is the
complicated clinical course of the condition, characterized by manic, depressive and mixed …

Objectives: This narrative review article provides an overview on the involvement of
microglia and the hypothalamic-pituitary-adrenal (HPA) axis in the pathophysiology of …

Bipolar disorder (BD) is a chronic mental illness characterized by mood fluctuations that
range from depressive lows to manic highs. Several studies have linked the downregulation …

Objectives Several recent studies have suggested that the physiopathology of bipolar
disorder (BD) is related to immune system alterations and inflammation. Lithium (Li) is a …