Phosphatidylinositide 3 kinases (PI3Ks) and their downstream mediators AKT and
mammalian target of rapamycin (mTOR) constitute the core components of the …

Abstract The PI3K/AKT signaling pathway is an essential node in mammalian cells that
controls cell growth, migration, proliferation, and metabolism. During the last decade, a …

The increasing availability of multi-omic platforms poses new challenges to data analysis.
Joint visualization of multi-omics data is instrumental in better understanding …

Cacumen Platycladi (CP) consists of the dried needles of Platycladus orientalis L.) Franco. It
was clinically demonstrated that it effectively regenerates hair, but the underlying …

Estrogen‐related receptor b (Esrrb) is part of a family of three orphan nuclear receptors with
broad expression profiles and a generic function in regulating energy metabolism in …

Wound healing involves a series of cellular and molecular processes to heal injured tissue.
Growth factors such as vascular endothelial growth factor (VEGF), and signalling pathways …

Human embryonic and induced pluripotent stem cells are self-renewing pluripotent stem
cells (PSC) that can differentiate into a wide range of specialized cells. Basic fibroblast …

Over the last 2 decades, induced pluripotent stem cells (iPSCs) have had various potential
applications in various medical research areas, from personalized medicine to disease …

Until recently, human embryonic stem cells (hESCs) were shown to exist in a state of primed
pluripotency, while mouse embryonic stem cells (mESCs) display a naive or primed …

Abstract Background PBX homeobox 1 (PBX1) is involved in the maintenance of the
pluripotency of human embryonic and hematopoietic stem cells; however, the effects of …