Benzodiazepines and medications acting on benzodiazepine receptors that do not have a
benzodiazepine structure (z-drugs) have been viewed by some experts and regulatory …

Benzodiazepines have been in use for over half a century. While they remain highly
prescribed, their unfavorable side-effect profile and abuse liability motivated a search for …

In pharmacoepidemiology, routinely collected data from electronic health records (including
primary care databases, registries, and administrative healthcare claims) are a resource for …

Background The high prevalence and long-term use of benzodiazepines (BZDs) treatment
are debated topics because of the risk they can cause to the patients. Despite the current …

Abstract Purpose Base de Datos para la Investigación Farmacoepidemiológica en Atención
Primaria (BIFAP) is a population based database administered by the AEMPS (Spanish …

Background Benzodiazepine use is associated with adverse drug events and higher
mortality. Known risk factors for benzodiazepine-related adverse events include lung …

Background Despite an increase in the prevalence of sleep problems, few studies have
investigated changes in the prescribing of drugs that are often used to manage insomnia …

Objectives To evaluate the risk of all cause mortality associated with initiating compared with
not initiating benzodiazepines in adults, and to address potential treatment barriers and …

Background Studies suggest that anticholinergic medication or benzodiazepine use could
increase dementia risk. We tested this hypothesis using data from a UK cohort study …

Objective To describe the trends in use of antidepressants (ADs), atypical antipsychotics
(AAPs), and benzodiazepines (BZDs) among high-, middle-, and low-income countries …