Antimicrobial resistance prediction in Neisseria gonorrhoeae: current status and future prospects

D Golparian, M Unemo - Expert Review of Molecular Diagnostics, 2022 - Taylor & Francis
Introduction Several nucleic acid amplification tests (NAATs), mostly PCRs, to detect
antimicrobial resistance (AMR) determinants and predict AMR in Neisseria gonorrhoeae are …

Advances in genotypic antimicrobialresistance testing: a comprehensive review

B Duan, X Zeng, J Peng - Science China Life Sciences, 2024 - Springer
Antimicrobial resistance (AMR) represents a substantial threat to global public health,
complicating the treatment of common infections and leading to prolonged illness and …

Application of nanopore sequencing technology in the clinical diagnosis of infectious diseases

LL Zhang, C Zhang, JP Peng - Biomedical and Environmental Sciences, 2022 - Elsevier
Infectious diseases are an enormous public health burden and a growing threat to human
health worldwide. Emerging or classic recurrent pathogens, or pathogens with resistant …

CRISPR-based platform for clinical diagnosis of Neisseria gonorrhoeae and simultaneous tracking of ceftriaxone-resistant FC428 clone

C Wang, L Xiu, Q Hu, R Zhong, X Guo, J Peng… - Chemical Engineering …, 2024 - Elsevier
The global dissemination of the ceftriaxone-resistant Neisseria gonorrhoeae FC428 clone
poses substantial challenges in the control and treatment of gonorrhoea, resulting in …

Multiplex PCR and Nanopore Sequencing of Genes Associated with Antimicrobial Resistance in Neisseria gonorrhoeae Directly from Clinical Samples

C Zhang, L Xiu, Y Li, L Sun, Y Li, Y Zeng… - Clinical …, 2021 - academic.oup.com
Background Antimicrobial resistance (AMR) of Neisseria gonorrhoeae has spread
worldwide. Rapid and comprehensive methods are needed to describe N. gonorrhoeae …

Development and application of Cas13a-based diagnostic assay for Neisseria gonorrhoeae detection and azithromycin resistance identification

H Luo, W Chen, Z Mai, J Yang, X Lin… - Journal of …, 2022 - academic.oup.com
Abstract Background Gonorrhoea, caused by Neisseria gonorrhoeae, has spread
worldwide. Strains resistant to most antibiotics, including ceftriaxone and azithromycin, have …

Multigeographic clinical assessment of a molecular diagnostic assay for detection of key codons to predict decreased susceptibility or resistance to cephalosporins in …

L Wang, Y Li, L Xiu, L Hu, J Huang… - Antimicrobial Agents …, 2024 - journals.asm.org
Cephalosporin resistance in Neisseria gonorrhoeae has severely compromised the efficacy
of World Health Organization (WHO)-recommended therapies. This study aimed to …

Typing of Neisseria gonorrhoeae isolates in Shenzhen, China, from 2014 to 2018 reveals the shift of genotypes significantly associated with antimicrobial resistance

Y Li, Y Li, L Xiu, Y Zeng, C Zhang, L Sun… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
The growing antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a serious global
threat to gonococcal therapy. Molecular typing is an ideal tool to reveal the association …

A Multiplex Molecular Assay for Detection of Six penA Codons To Predict Decreased Susceptibility to Cephalosporins in Neisseria gonorrhoeae

Y Li, L Zhang, L Xiu, D Wang, Y Zeng… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
The emerging cephalosporin-resistant Neisseria gonorrhoeae poses an urgent threat to the
continued efficacy of the last-line monotherapy for gonorrhea. Consequently, high …

Advances in antimicrobial resistance testing

C Zhang, L Sun, D Wang, Y Li, L Zhang, L Wang… - Advances in Clinical …, 2022 - Elsevier
Antimicrobial resistance (AMR), especially bacterial AMR, poses a global threat to public
health and has become a huge obstacle to the effective control of related infectious …