The human papillomavirus (HPV) is a DNA tumor virus that infects cutaneous and mucosal
epithelia where high-risk (HR) HPV infections lead to cervical, oropharyngeal, and …

The E2 protein encoded by human papillomaviruses (HPV) is a sequence-specific DNA-
binding protein that recruits viral and cellular proteins. Bromodomain-containing protein 4 …

Papillomaviruses (PV) replicate in undifferentiated keratinocytes at low levels and to high
levels in differentiated cells. The restricted replication in undifferentiated cells is mainly due …

The papillomavirus (PV) E2 protein coordinates viral transcription and genome replication.
Following a strategy to identify amino acids in E2 that are posttranslationally modified, we …

Human papillomaviruses are small DNA tumor viruses that infect cutaneous and mucosal
epithelia. The viral lifecycle is linked to the differentiation status of the epithelium. During …

The papillomavirus (PV) E2 protein is a DNA binding, protein interaction platform that
recruits viral and host factors necessary for transcription and replication. We recently …

In this study, a virtual screening pipeline comprising ligand-based and structure-based
approaches was established and applied for the identification of dual PTP1B and ACP1 …

The papillomavirus (PV) E2 protein is a critical regulator of viral transcription and genome
replication. We previously reported that tyrosine (Y) 138 of HPV-31 E2 is phosphorylated by …

The papillomavirus E2 protein regulates transcription, replication, and nuclear retention of
viral genomes. Phosphorylation of E2 in the hinge region has been suggested to modulate …

The papillomavirus (PV) E2 protein activates transcription and replication by recruiting
cellular proteins and the E1 DNA helicase to their binding sites in the viral genome. We …