Arsenic is a known toxin and carcinogen that is present in industrial settings and in the
environment. The mechanisms of disease initiation and progression are not fully …

Exposure to arsenic in contaminated drinking water is an emerging public health problem
that impacts more than 200 million people worldwide. Accumulating lines of evidence from …

Abstract The EFSA Panel on Contaminants in the Food Chain (CONTAM Panel) assessed
the risks to human health related to the presence of arsenic in food. More than 100,000 …

Epidemiological evidence suggests that exposure to certain metals causes carcinogenesis.
The mechanisms of metal-induced carcinogenesis have been pursued in chemical …

Vitamin D is produced in skin by UVB radiation (290–320 nm) acting on 7-
dehydrocholesterol. The hypotheses that the active vitamin D hormone, 1, 25 …

Arsenite was shown to inhibit pyruvate dehydrogenase (PDH) activity through binding to
vicinal dithiols in pure enzyme and tissue extract. However, no data are available on how …

Exposure to ultraviolet radiation (UVR) can lead to a range of deleterious responses in the
skin. An important form of damage is the DNA photolesion cyclobutane pyrimidine dimer …

Today, there is a controversial debate in many scientific and public communities on how
much sunlight is appropriate to balance between the positive and negative effects of solar …

Arsenic-induced tissue damage is a major concern to the human population. An impaired
antioxidant defense mechanism followed by oxidative stress is the major cause of arsenic …

We previously reported that the natural hormone 1, 25dihydroxyvitamin D3 (1, 25 (OH) 2D3)
protects human skin cells from ultraviolet radiation (UVR)-induced apoptosis. UVR-induced …